E2F1 抗体
(E2F Transcription Factor 1 (E2F1))
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008].
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recommended
E2F1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 1D12 unconjugated Recombinant Antibody
recommended
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Latest Publications for our E2F1 抗体
: "Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo." in: International journal of oncology, Vol. 57, Issue 3, pp. 697-706, (2020) (PubMed).: "Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting." in: Scientific reports, Vol. 7, Issue 1, pp. 10237, (2019) (PubMed).
: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." in: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).
: "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." in: Environmental science and pollution research international, Vol. 25, Issue 4, pp. 3423-3434, (2018) (PubMed).
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).
: "E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair." in: Oncotarget, Vol. 7, Issue 18, pp. 26275-92, (2018) (PubMed).
: "Dependence of p53-deficient cells on the DHX9 DExH-box helicase." in: Oncotarget, Vol. 8, Issue 19, pp. 30908-30921, (2017) (PubMed).
: "Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24538-24550, (2017) (PubMed).
: "Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease." in: Aging, Vol. 8, Issue 2, pp. 272-90, (2016) (PubMed).
: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).
Aliases for E2F1 抗体
E2F transcription factor 1 (E2f1) 抗体E2F transcription factor 1 (E2F1) 抗体
E2F transcription factor 1 L homeolog (e2f1.L) 抗体
ATE2FB 抗体
CG6376 抗体
dE2F 抗体
dE2f 抗体
dE2F1 抗体
dE2f1 抗体
de2f1 抗体
def21 抗体
DmE2F-1 抗体
Dmel\\CG6376 抗体
Dp 抗体
drosE2F1 抗体
DRTF1/E2F 抗体
E(Sev-CycE)3A 抗体
E(var)3-93E 抗体
E(var)3-95E 抗体
E(var)93E 抗体
E2F 抗体
e2f 抗体
E2F-1 抗体
E2F1 抗体
E2f1 抗体
e2f1 抗体
E2FB 抗体
E2FB TRANSCRIPTION FACTOR 抗体
E2F TRANSCRIPTION FACTOR-1 E2F1 抗体
E2F transcription factor 1 抗体
Evar(3)164 抗体
l(3)07172 抗体
l(3)j3B1 抗体
l(3)j3C2 抗体
l(3)rM729 抗体
mKIAA4009 抗体
RBAP1 抗体
RBBP3 抗体
RBP3 抗体
xE2F 抗体
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