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Dystrophin 蛋白

(Dystrophin (DMD))

The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].

recommended

Dystrophin Protein (DMD) (AA 1-635) (GST tag) (ABIN1351717)

DMD 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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DMD 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % WB, SDS, Imm, PC

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DMD 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, Imm, PC

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Dystrophin 蛋白 by Origin

Find Dystrophin 蛋白 for a variety of species such as anti-Human Dystrophin, anti-Mouse Dystrophin. The species listed below are among those available. Click on a link to go to the corresponding products.

Dystrophin 蛋白 by Source

Here you will find Dystrophin 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Dystrophin 蛋白 by 蛋白类型

Here you can find Dystrophin 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Dystrophin 蛋白 by 应用范围

Find Dystrophin 蛋白 validated for a specific application such as WB, SDS, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Dystrophin 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Dystrophin Protein (DMD) (AA 1-635) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351717

Quantity 10 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 253-597) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7420834

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 3048-3328) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394210

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 3059-3314) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394213

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009210

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719890

Quantity 20 μg

Datasheet Datasheet

Aliases for Dystrophin 蛋白

dystrophin (DMD) 蛋白
dystrophin (LOC708073) 蛋白
dystrophin, gene 1 L homeolog (dmd.1.L) 蛋白
dystrophin (LOC465557) 蛋白
dystrophin, gene 1 (dmd.1) 蛋白
dystrophin (dmd) 蛋白
dystrophin, muscular dystrophy (Dmd) 蛋白
dystrophin (Dmd) 蛋白
Dystrophin (Dys) 蛋白
BMD 蛋白
cb664 蛋白
CG7240 蛋白
CG7243 蛋白
CG7344 蛋白
CG17750 蛋白
CG31175 蛋白
CG34157 蛋白
CMD3B 蛋白
det 蛋白
DKFZp459C1629 蛋白
DKFZp468A1620 蛋白
DLP 蛋白
DLP1 蛋白
DLP2 蛋白
DLP3 蛋白
DLP186 蛋白
DMD 蛋白
Dmd 蛋白
dmd 蛋白
DmDLP 蛋白
dmDLP 蛋白
dmDp186 蛋白
DmDYS 蛋白
dmDys 蛋白
Dmel\\CG34157 蛋白
DNADMD1 蛋白
Dp71 蛋白
Dp117 蛋白
Dp186 蛋白
Dp205 蛋白
Dp427 蛋白
DXS142 蛋白
DXS164 蛋白
DXS206 蛋白
DXS230 蛋白
DXS239 蛋白
DXS268 蛋白
DXS269 蛋白
DXS270 蛋白
DXS272 蛋白
DXSmh7 蛋白
DXSmh9 蛋白
dys 蛋白
GI3046716 蛋白
IDLP 蛋白
im:6911785 蛋白
mdx 蛋白
MGC79631 蛋白
MGC83347 蛋白
pke 蛋白
RATDMD 蛋白
zfDYS 蛋白
zgc:110165 蛋白

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Dystrophin 蛋白 by Origin

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Dystrophin 蛋白 by 蛋白类型

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Popular Dystrophin 蛋白

Aliases for Dystrophin 蛋白

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