Dystrophin 抗体
(Dystrophin (DMD))
The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].
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Dystrophin 抗体 by 适用
Find Dystrophin 抗体 for a variety of species such as anti-Human Dystrophin, anti-Mouse Dystrophin, anti-Rat Dystrophin. The species listed below are among those available. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 应用范围
Find Dystrophin 抗体 validated for a specific application such as IHC, WB, ELISA, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 抗体来源
Find Dystrophin 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 抗原表位
Find Dystrophin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Dystrophin 抗体. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 克隆
Find Dystrophin 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Dystrophin 抗体 by 标记
Find Dystrophin 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Quantity
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Quantity
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Quantity
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN7433720
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN7426295
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
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Latest Publications for our Dystrophin 抗体
: "In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy." in: Disease models & mechanisms, Vol. 13, Issue 2, (2019) (PubMed).: "Immunohistochemical study on dystrophin expression in CAD-related sudden cardiac death: a marker of early myocardial ischaemia." in: International journal of legal medicine, Vol. 132, Issue 5, pp. 1333-1339, (2018) (PubMed).
: "Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly ..." in: Circulation. Heart failure, Vol. 9, Issue 1, pp. e002081, (2016) (PubMed).
: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).
: "Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise." in: Cellular signalling, Vol. 28, Issue 9, pp. 1205-15, (2016) (PubMed).
: "A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis." in: Journal of molecular and cellular cardiology, Vol. 98, pp. 37-47, (2016) (PubMed).
: "Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma." in: Cancer genetics, Vol. 205, Issue 5, pp. 232-41, (2012) (PubMed).
: "Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 663-8, (1993) (PubMed).
: "A quantitative ELISA for dystrophin." in: Journal of immunological methods, Vol. 161, Issue 1, pp. 23-8, (1993) (PubMed).
Aliases for Dystrophin 抗体
dystrophin (DMD) 抗体dystrophin (LOC708073) 抗体
dystrophin, gene 1 L homeolog (dmd.1.L) 抗体
dystrophin (LOC465557) 抗体
dystrophin, gene 1 (dmd.1) 抗体
dystrophin (dmd) 抗体
dystrophin, muscular dystrophy (Dmd) 抗体
dystrophin (Dmd) 抗体
Dystrophin (Dys) 抗体
BMD 抗体
cb664 抗体
CG7240 抗体
CG7243 抗体
CG7344 抗体
CG17750 抗体
CG31175 抗体
CG34157 抗体
CMD3B 抗体
det 抗体
DKFZp459C1629 抗体
DKFZp468A1620 抗体
DLP 抗体
DLP1 抗体
DLP2 抗体
DLP3 抗体
DLP186 抗体
DMD 抗体
Dmd 抗体
dmd 抗体
DmDLP 抗体
dmDLP 抗体
dmDp186 抗体
DmDYS 抗体
dmDys 抗体
Dmel\\CG34157 抗体
DNADMD1 抗体
Dp71 抗体
Dp117 抗体
Dp186 抗体
Dp205 抗体
Dp427 抗体
DXS142 抗体
DXS164 抗体
DXS206 抗体
DXS230 抗体
DXS239 抗体
DXS268 抗体
DXS269 抗体
DXS270 抗体
DXS272 抗体
DXSmh7 抗体
DXSmh9 抗体
dys 抗体
GI3046716 抗体
IDLP 抗体
im:6911785 抗体
mdx 抗体
MGC79631 抗体
MGC83347 抗体
pke 抗体
RATDMD 抗体
zfDYS 抗体
zgc:110165 抗体
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