Dystroglycan 抗体
(Dystroglycan 1 (DAG1))
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
recommended
recommended
DAG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33752 unconjugated
recommended
DAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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Find available monoclonal or polyclonal Dystroglycan 抗体. Click on a link to go to the corresponding products.
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Popular Dystroglycan 抗体
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Cat. No.
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Reactivity
Human
Application
WB, ICC, IHC (p), IF
Validations
- (1)
- (4)
Cat. No.
ABIN2856020
Quantity
100 μL
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Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN658022
Quantity
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Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7434920
Quantity
100 μL
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Datasheet
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Application
WB, ELISA
Validations
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Cat. No.
ABIN560555
Quantity
100 μg
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Datasheet
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Human
Application
WB, ELISA, IHC, IF, FACS
Validations
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Cat. No.
ABIN571179
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
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Cat. No.
ABIN7139811
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6261217
Quantity
100 μL
Datasheet
Datasheet
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Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
ABIN6743420
Quantity
100 μL
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Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rabbit, Rat
Application
WB
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Reactivity
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Application
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Validations
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Cat. No.
ABIN7538842
Quantity
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Datasheet
Reactivity
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WB, IF
Validations
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Cat. No.
ABIN6139391
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
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Validations
- (2)
Cat. No.
ABIN2773882
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No.
ABIN753463
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN753465
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IF (cc), IF (p)
Validations
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ABIN5000981
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Dystroglycan 抗体
: "Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice." in: eLife, Vol. 8, (2019) (PubMed).: "Detection of variants in dystroglycanopathy-associated genes through the application of targeted whole-exome sequencing analysis to a large cohort of patients with unexplained limb-girdle muscle ..." in: Skeletal muscle, Vol. 8, Issue 1, pp. 23, (2018) (PubMed).
: "Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone." in: Journal of neuropathology and experimental neurology, Vol. 76, Issue 11, pp. 969-977, (2017) (PubMed).
: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).
: "Virus entry. Lassa virus entry requires a trigger-induced receptor switch." in: Science (New York, N.Y.), Vol. 344, Issue 6191, pp. 1506-10, (2014) (PubMed).
: "The N-terminal domain of ?-dystroglycan, released as a 38 kDa protein, is increased in cerebrospinal fluid in patients with Lyme neuroborreliosis." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 494-9, (2011) (PubMed).
: "Localization of phospho-beta-dystroglycan (pY892) to an intracellular vesicular compartment in cultured cells and skeletal muscle fibers in vivo." in: Biochemistry, Vol. 42, Issue 23, pp. 7110-23, (2003) (PubMed).
: "The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane." in: The Journal of cell biology, Vol. 152, Issue 3, pp. 435-50, (2001) (PubMed).
: "Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family members." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38048-58, (2000) (PubMed).
: "Adhesion-dependent tyrosine phosphorylation of (beta)-dystroglycan regulates its interaction with utrophin." in: Journal of cell science, Vol. 113 ( Pt 10), pp. 1717-26, (2000) (PubMed).
Aliases for Dystroglycan 抗体
DystroGlycaN (dgn-1) 抗体dystroglycan 1 L homeolog (dag1.L) 抗体
DystroGlycaN (dgn-2) 抗体
DystroGlycaN (dgn-3) 抗体
dystroglycan 1 (DAG1) 抗体
dystroglycan 1 S homeolog (dag1.S) 抗体
dystroglycan 1 (Dag1) 抗体
dystroglycan 1 (dag1) 抗体
Dystroglycan (Dg) 抗体
dystroglycan (LOC408826) 抗体
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