Dystroglycan 产品
(Dystroglycan 1 (DAG1))
Categories
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
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Featured Dystroglycan Categories
Dystroglycan 抗体
High quality antibodies with extensive validation data.
Dystroglycan ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Dystroglycan 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Dystroglycan 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IHC (p), IF
Validations
- (1)
- (4)
Cat. No.
ABIN2856020
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN658022
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7434920
Quantity
100 μL
Datasheet
Datasheet
Recommended Dystroglycan ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6955481
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955482
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955483
Quantity
96 tests
Datasheet
Datasheet
Recommended Dystroglycan 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1351078
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122728
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396379
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Dystroglycan Products
: "Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity." in: British journal of pharmacology, Vol. 176, Issue 16, pp. 2877-2893, (2020) (PubMed).: "The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury." in: Molecular neurobiology, Vol. 55, Issue 2, pp. 1284-1298, (2019) (PubMed).
: "Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice." in: eLife, Vol. 8, (2019) (PubMed).
: "Detection of variants in dystroglycanopathy-associated genes through the application of targeted whole-exome sequencing analysis to a large cohort of patients with unexplained limb-girdle muscle ..." in: Skeletal muscle, Vol. 8, Issue 1, pp. 23, (2018) (PubMed).
: "PEDF protects cardiomyocytes by promoting FUNDC1‑mediated mitophagy via PEDF-R under hypoxic condition." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3394-3404, (2018) (PubMed).
: "Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone." in: Journal of neuropathology and experimental neurology, Vol. 76, Issue 11, pp. 969-977, (2017) (PubMed).
: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).
: "Pigment Epithelium-Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF-R)." in: Journal of the American Heart Association, Vol. 5, Issue 7, (2016) (PubMed).
: "A High-Throughput Assay for the Detection of α-Dystroglycan N-Terminus in Human Uterine Fluid to Determine Uterine Receptivity." in: Journal of biomolecular screening, Vol. 21, Issue 4, pp. 408-13, (2016) (PubMed).
: "Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression." in: The Journal of biological chemistry, Vol. 291, Issue 13, pp. 7004-16, (2016) (PubMed).
Synonyms and alternative names related to Dystroglycan
DystroGlycaN (dgn-1), dystroglycan 1 L homeolog (dag1.L), DystroGlycaN (dgn-2), DystroGlycaN (dgn-3), dystroglycan 1 (DAG1), dystroglycan 1 S homeolog (dag1.S), dystroglycan 1 (Dag1), dystroglycan 1 (dag1), Dystroglycan (Dg), dystroglycan (LOC408826), clusterin (Clu), lymphocyte antigen 6 complex (Ly6), 156DAG, 156dag, A3a, a3a, AGRNR, agrnr, Ala-1, APOJ, atu, CG18250, CLI, CT41273, D9Wsu13e, DAG, dag, dag1, DAG1, dg, DG, dgn, DmDG, Dmel\\CG18250, Dp71, Dp427, dys, GB14967, H9/25, LOC398500, Ly-6, Ly-27, Ly27, MDDGC7, MDDGC9, MGC53537, RAB7, RATTRPM2B, SGP-2, SGP2, SP-40, SP40, TRPM-2, Trpm2, TRPM2B, Trpmb, wu:fb83d06, wu:fi25f06, wu:fi37b08, zgc:109786Protein level used designations for Dystroglycan
- DystroGlycaN family member (dgn-1)
- dystroglycan
- DystroGlycaN family member (dgn-2)
- DystroGlycaN family member (dgn-3)
- dystrophin-associated glycoprotein 1
- dystroglycan 1
- dystroglycan 1 (dystrophin-associated glycoprotein 1)
- RAB7, member RAS oncogene family
- glycine cleavage system T-protein
- alpha-dystroglycan
- beta-dystroglycan
- dystrophin associated glycoprotein 1
- CG18250-PA
- CG18250-PB
- CG18250-PC
- CG18250-PD
- Dg-PA
- Dg-PB
- Dg-PC
- Dg-PD
- atsugari
- dystroglycan-like
- dimeric acid glycoprotein
- sulfated glycoprotein 2
- testosterone repressed prostate message 2
- testosterone-repressed prostate message
- testostrone-repressed prostate message 2
- dystrophin-associated glycoprote
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