Dynactin 1 抗体
(Dynactin 1 (DCTN1))
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008].
recommended
Verified DCTN1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
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Popular Dynactin 1 抗体
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Cat. No.
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Quantity
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WB, ELISA, IHC (p), IHC (fro)
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Cat. No.
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Quantity
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Cat. No.
ABIN893649
Quantity
100 μL
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WB, IF (cc), IF (p)
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Cat. No.
ABIN893647
Quantity
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Quantity
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Latest Publications for our Dynactin 1 抗体
: "The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization." in: Molecular biology of the cell, pp. mbcE18020108, (2018) (PubMed).: "Temporal changes in expression of connexin 43 after load-induced hypertrophy in vitro." in: American journal of physiology. Heart and circulatory physiology, Vol. 296, Issue 3, pp. H806-14, (2009) (PubMed).
: "Anthrax toxin rafts into cells." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 295-6, (2003) (PubMed).
: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).
: "NudC associates with Lis1 and the dynein motor at the leading pole of neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 24, pp. RC187, (2001) (PubMed).
: "Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport." in: The Journal of cell biology, Vol. 153, Issue 7, pp. 1499-509, (2001) (PubMed).
: "Dynactin increases the processivity of the cytoplasmic dynein motor." in: Nature cell biology, Vol. 2, Issue 1, pp. 20-4, (2000) (PubMed).
: "Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by fluorescence in situ hybridization." in: Genomics, Vol. 31, Issue 3, pp. 398-9, (1997) (PubMed).
: "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1634-8, (1995) (PubMed).
: "Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued." in: Nature, Vol. 351, Issue 6327, pp. 579-83, (1991) (PubMed).
Aliases for Dynactin 1 抗体
dynactin subunit 1 (DCTN1) 抗体dynactin subunit 1 (Dctn1) 抗体
dynactin 1 (Dctn1) 抗体
Dynactin 1, p150 subunit (DCTN1-p150) 抗体
dynactin subunit 1 L homeolog (dctn1.L) 抗体
AL022633 抗体
CG9206 抗体
Chip150 抗体
DAP-150 抗体
DCTN1 抗体
DKFZp469C1813 抗体
Dmel\\CG9206 抗体
DP-150 抗体
Dynactin-1 抗体
DYNA_DROME 抗体
FCP-D 抗体
Glu 抗体
Glued 抗体
glued 抗体
P135 抗体
p150 抗体
P150 抗体
p150/Glued 抗体
p150/glued 抗体
p150
P150[Glued] 抗体
p150[Glued] 抗体
p150[glued] 抗体
t1 抗体
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