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DUSP9 产品

(Dual Specificity Phosphatase 9 (DUSP9))

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008].

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Featured DUSP9 Categories

DUSP9 抗体

High quality antibodies with extensive validation data.

DUSP9 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DUSP9 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DUSP9 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6257141
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7150786
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN515112
Quantity 100 μg
Datasheet Datasheet

Recommended DUSP9 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966430
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955469
Quantity 96 tests
Datasheet Datasheet

Recommended DUSP9 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352146
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352148
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398728
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DUSP9 Products

Hui, Wang, Zhou, Ma, Yan, Zhang, Wang, Yu: "Association Between MKP-1, BDNF, and Gonadal Hormones with Depression on Perimenopausal Women." in: Journal of women's health (2002), (2015) (PubMed).

Emanuelli, Eberlé, Suzuki, Kahn: "Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3545-50, (2008) (PubMed).

Keyse: "Dual-specificity MAP kinase phosphatases (MKPs) and cancer." in: Cancer metastasis reviews, Vol. 27, Issue 2, pp. 253-61, (2008) (PubMed).

Christie, Williams, Macisaac, Dickinson, Rosewell, Keyse: "The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8323-33, (2005) (PubMed).

Synonyms and alternative names related to DUSP9

dual specificity phosphatase 9 (DUSP9), dual specificity phosphatase 9 (Dusp9), Dusp4, DUSP9, MKP-4, MKP4, Mpk4, Pyst3

Protein level used designations for DUSP9

  • dual specificity protein phosphatase 9
  • map kinase phosphatase 4
  • mitogen-activated protein kinase phosphatase 4
  • serine/threonine specific protein phosphatase
  • dual-specificity MAP kinase phosphatase 4
  • dual specificity phosphatase 9
  • LOW QUALITY PROTEIN: dual specificity protein phosphatase 9
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