DUSP4 抗体
(Dual Specificity Phosphatase 4 (DUSP4))
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008].
recommended
recommended
DUSP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
recommended
DUSP4 抗体 by 适用
Find DUSP4 抗体 for a variety of species such as anti-Human DUSP4, anti-Mouse DUSP4, anti-Rat DUSP4. The species listed below are among those available. Click on a link to go to the corresponding products.
DUSP4 抗体 by 抗体来源
Find DUSP4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
DUSP4 抗体 by 克隆形成能力
Find available monoclonal or polyclonal DUSP4 抗体. Click on a link to go to the corresponding products.
DUSP4 抗体 by 克隆
Find DUSP4 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular DUSP4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN515105
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6263269
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, PLA
Validations
- (3)
Cat. No.
ABIN515104
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN560663
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7150773
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7239902
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN3016540
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN392861
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (1)
Cat. No.
ABIN3185575
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN6755360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN1533856
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN360778
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN735383
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN735385
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN5006898
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our DUSP4 抗体
: "Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers." in: International journal of oncology, Vol. 45, Issue 6, pp. 2250-66, (2014) (PubMed).: "Dual specificity phosphatase 6 as a predictor of invasiveness in papillary thyroid cancer." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 167, Issue 1, pp. 93-101, (2012) (PubMed).
: "Dual-specificity MAP kinase phosphatases (MKPs) and cancer." in: Cancer metastasis reviews, Vol. 27, Issue 2, pp. 253-61, (2008) (PubMed).
: "Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress." in: The Journal of biological chemistry, Vol. 282, Issue 39, pp. 28395-407, (2007) (PubMed).
: "Mitogen-activated protein kinase phosphatase 2: a novel transcription target of p53 in apoptosis." in: Cancer research, Vol. 66, Issue 12, pp. 6033-9, (2006) (PubMed).
: "Cell transformation by v-Jun deactivates ERK MAP kinase signalling." in: Oncogene, Vol. 21, Issue 42, pp. 6540-8, (2002) (PubMed).
: "Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically." in: The Journal of biological chemistry, Vol. 276, Issue 31, pp. 29440-9, (2001) (PubMed).
: "Mitogen-activated protein kinase phosphatases inactivate stress-activated protein kinase pathways in vivo." in: The Journal of biological chemistry, Vol. 272, Issue 7, pp. 4568-75, (1997) (PubMed).
: "A novel mitogen-activated protein kinase phosphatase. Structure, expression, and regulation." in: The Journal of biological chemistry, Vol. 270, Issue 24, pp. 14587-96, (1995) (PubMed).
Aliases for DUSP4 抗体
dual specificity phosphatase 4 (dusp4) 抗体dual specificity phosphatase 4 (DUSP4) 抗体
dual specificity phosphatase 4 S homeolog (dusp4.S) 抗体
dual specificity phosphatase 4 (Dusp4) 抗体
2700078F24Rik 抗体
AI844617 抗体
BB104621 抗体
DUSP4 抗体
E130306H24Rik 抗体
hvh2 抗体
HVH2 抗体
MGC131045 抗体
mkp-2 抗体
MKP-2 抗体
Mkp-2 抗体
mkp2 抗体
MKP2 抗体
Mkp2 抗体
typ 抗体
TYP 抗体
zgc:55423 抗体
您还需要查找其他产品吗？
You are here:
