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DUSP2 产品

(Dual Specificity Phosphatase 2 (DUSP2))

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008].

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Featured DUSP2 Categories

DUSP2 抗体

High quality antibodies with extensive validation data.

DUSP2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended DUSP2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7190518
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7266847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN653027
Quantity 400 μL
Datasheet Datasheet

Recommended DUSP2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1130791
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1130792
Quantity 96 tests
Datasheet Datasheet

Recommended DUSP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3079280
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3121449
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DUSP2 Products

Volk, Li, Xin, You, Zhang, Liu, Xiao, Breslin, Li, Wei, Schmidt, Li, Zhang, Kuo, Nand, Zhang, Chen, Zhang: "Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML." in: The Journal of experimental medicine, Vol. 211, Issue 6, pp. 1093-108, (2014) (PubMed).

Chappell, Sun, Singh, Dalton: "MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7." in: Genes & development, Vol. 27, Issue 7, pp. 725-33, (2013) (PubMed).

Synonyms and alternative names related to DUSP2

dual specificity phosphatase 2 (dusp2), dual specificity phosphatase 2 (DUSP2), dual specificity phosphatase 2 (Dusp2), PAC-1, PAC1, wu:fj40g04, zgc:91929

Protein level used designations for DUSP2

  • dual specificity protein phosphatase 2
  • dual specificity protein phosphatase PAC-1
  • dual-specificity phosphatase 2
  • serine/threonine specific protein phosphatase
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