DUSP10 抗体
(Dual Specificity Phosphatase 10 (DUSP10))
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique\; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
DUSP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
recommended
DUSP10 抗体 by Grade
Find DUSP10 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
DUSP10 抗体 by 应用范围
Find DUSP10 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
DUSP10 抗体 by 抗体来源
Find DUSP10 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
DUSP10 抗体 by 抗原表位
Find DUSP10 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
DUSP10 抗体 by 克隆形成能力
Find available monoclonal or polyclonal DUSP10 抗体. Click on a link to go to the corresponding products.
DUSP10 抗体 by 克隆
Find DUSP10 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular DUSP10 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN564881
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6257139
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), ICC, IF
Validations
- (3)
Cat. No.
ABIN2855915
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN392871
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881272
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN3185578
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN184694
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6742090
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
Cat. No.
ABIN6139859
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN634409
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN360788
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
Cat. No.
ABIN1714147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1700645
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN1697021
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our DUSP10 抗体
: "Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation." in: Cancer research, Vol. 71, Issue 16, pp. 5535-45, (2011) (PubMed).: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
: "Asbestos-induced MKP-3 expression augments TNF-alpha gene expression in human monocytes." in: American journal of respiratory cell and molecular biology, Vol. 39, Issue 1, pp. 113-23, (2008) (PubMed).
: "Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress." in: The Journal of biological chemistry, Vol. 282, Issue 39, pp. 28395-407, (2007) (PubMed).
: "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity." in: Molecular and cellular biology, Vol. 25, Issue 19, pp. 8619-30, (2005) (PubMed).
: "MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases." in: Oncogene, Vol. 18, Issue 50, pp. 6981-8, (2000) (PubMed).
: "Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19949-56, (1999) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Aliases for DUSP10 抗体
dual specificity phosphatase 10 (DUSP10) 抗体dual specificity phosphatase 10 (Dusp10) 抗体
2610306G15Rik 抗体
AI158871 抗体
DUSP10 抗体
MKP-5 抗体
Mkp-5 抗体
MKP5 抗体
Mkp5 抗体
您还需要查找其他产品吗？
You are here:
