DSCR4 产品
(Down Syndrome Critical Region Gene 4 (DSCR4))
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The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq, Jul 2008].
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: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).Synonyms and alternative names related to DSCR4
Down syndrome critical region 4 (DSCR4), DCRB, DSCRBProtein level used designations for DSCR4
- Down syndrome critical region protein 4
- Down syndrome critical region protein B
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