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DRD3 产品

(Dopamine Receptor D3 (DRD3))
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008].

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Featured DRD3 Categories

DRD3 抗体

High quality antibodies with extensive validation data.

DRD3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DRD3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DRD3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN733808
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3015510
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7043109
Quantity 25 μL
Datasheet Datasheet

Recommended DRD3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966418
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955448
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512480
Quantity 96 tests
Datasheet Datasheet

Recommended DRD3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392698
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7538216
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our DRD3 Products

Micheli, Bernardelli, Bianchi, Braggio, Castelletti, Cavallini, Cavanni, Cremonesi, Dal Cin, Feriani, Oliosi, Semeraro, Tarsi, Tomelleri, Wong, Visentini, Zonzini, Heidbreder: "1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists." in: Bioorganic & medicinal chemistry, Vol. 24, Issue 8, pp. 1619-36, (2016) (PubMed).

Micheli, Bacchi, Braggio, Castelletti, Cavallini, Cavanni, Cremonesi, Dal Cin, Feriani, Gehanne, Kajbaf, Marchió, Nola, Oliosi, Pellacani, Perdonà, Sava, Semeraro, Tarsi, Tomelleri, Wong, Visentini et al.: "1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists. ..." in: Journal of medicinal chemistry, Vol. 59, Issue 18, pp. 8549-76, (2016) (PubMed).

Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: "Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells." in: Acta pharmacologica Sinica, Vol. 35, Issue 7, pp. 889-98, (2014) (PubMed).

Synonyms and alternative names related to DRD3

dopamine receptor D3 (drd3), dopamine receptor D3 (DRD3), dopamine receptor D3 (Drd3), D3DR, D3R, DRD3, ETM1, FET1

Protein level used designations for DRD3

  • D(3) dopamine receptor
  • dopamine receptor D3
  • dopamine receptor 3
  • dopamine D3 receptor
  • dopaminergic receptor D3
  • essential tremor 1
  • D3 receptor
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