DRAP1 产品
(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
Categories
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].
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Featured DRAP1 Categories
DRAP1 抗体
High quality antibodies with extensive validation data.
DRAP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DRAP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DRAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN564619
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Goat, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6741729
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7266844
Quantity
100 μL
Datasheet
Datasheet
Recommended DRAP1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1130683
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1130684
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1130685
Quantity
96 tests
Datasheet
Datasheet
Recommended DRAP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352006
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352008
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (5)
- (1)
Cat. No.
ABIN1046948
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DRAP1 Products
: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).
: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).
Synonyms and alternative names related to DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha) (drap1), DR1 associated protein 1 (DRAP1), Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1), Dr1 associated protein 1 (Drap1), 2310074H19Rik, DRAP1, fb26e10, NC2-alpha, wu:fb26e10, zgc:56003, zgc:77337Protein level used designations for DRAP1
- dr1-associated corepressor
- DR1-associated protein 1 (negative cofactor 2 alpha)
- NC2-alpha
- dr1-associated protein 1
- negative co-factor 2-alpha
- negative cofactor 2 alpha
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