DRAM 产品
(DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
Categories
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008].
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Featured DRAM Categories
DRAM 抗体
High quality antibodies with extensive validation data.
DRAM ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended DRAM 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7150140
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6745422
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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WB
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Cat. No.
ABIN7266817
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100 μL
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Recommended DRAM ELISA试剂盒
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Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966397
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN2947054
Quantity
96 tests
Datasheet
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Reactivity
Mouse
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Cat. No.
ABIN6224930
Quantity
96 tests
Datasheet
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Recommended DRAM 蛋白
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Reactivity
Source
Validations
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Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7547259
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7561322
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
Cat. No.
ABIN3103309
Quantity
250 μg
Datasheet
Datasheet
Latest Publications for our DRAM Products
: "Analysis of Proapoptotic Protein Trafficking to and from Mitochondria." in: Methods in molecular biology (Clifton, N.J.), Vol. 2310, pp. 161-178, (2021) (PubMed).: "Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells." in: Autophagy, Vol. 16, Issue 2, pp. 313-333, (2020) (PubMed).
: "Analysis of pro-apoptotic protein trafficking to and from mitochondria." in: Methods in molecular biology (Clifton, N.J.), Vol. 1241, pp. 163-80, (2015) (PubMed).
: "TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells." in: Cancer letters, Vol. 336, Issue 2, pp. 370-8, (2013) (PubMed).
: "Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity." in: Journal of pineal research, Vol. 52, Issue 1, pp. 80-92, (2012) (PubMed).
: "Sexual dimorphism of autophagy in Syrian hamster Harderian gland culminates in a holocrine secretion in female glands." in: Autophagy, Vol. 5, Issue 7, pp. 1004-17, (2010) (PubMed).
: "DRAM links autophagy to p53 and programmed cell death." in: Autophagy, Vol. 3, Issue 1, pp. 72-4, (2007) (PubMed).
: "DRAM, a p53-induced modulator of autophagy, is critical for apoptosis." in: Cell, Vol. 126, Issue 1, pp. 121-34, (2006) (PubMed).
: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).
Synonyms and alternative names related to DRAM
DNA damage regulated autophagy modulator 1 (DRAM1), DNA-damage regulated autophagy modulator 1 (Dram1), DNA damage regulated autophagy modulator 1 L homeolog (dram1.L), 1200002N14Rik, DRAM, Dram, dram, DRAM1Protein level used designations for DRAM
- DNA-damage regulated autophagy modulator 1
- DNA damage-regulated autophagy modulator protein 1
- damage-regulated autophagy modulator
- Damage-regulated autophagy modulator
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