DRAM 产品
(DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
Categories
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008].
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Featured DRAM Categories
DRAM 抗体
High quality antibodies with extensive validation data.
DRAM ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended DRAM 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7150140
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6745422
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7266817
Quantity
100 μL
Datasheet
Datasheet
Recommended DRAM ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966397
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6224930
Quantity
96 tests
Datasheet
Datasheet
Recommended DRAM 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3129628
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3103309
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DRAM Products
: "TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells." in: Cancer letters, Vol. 336, Issue 2, pp. 370-8, (2013) (PubMed).: "DRAM links autophagy to p53 and programmed cell death." in: Autophagy, Vol. 3, Issue 1, pp. 72-4, (2007) (PubMed).
: "DRAM, a p53-induced modulator of autophagy, is critical for apoptosis." in: Cell, Vol. 126, Issue 1, pp. 121-34, (2006) (PubMed).
: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).
Synonyms and alternative names related to DRAM
DNA damage regulated autophagy modulator 1 (DRAM1), DNA-damage regulated autophagy modulator 1 (Dram1), DNA damage regulated autophagy modulator 1 L homeolog (dram1.L), 1200002N14Rik, DRAM, Dram, dram, DRAM1Protein level used designations for DRAM
- DNA-damage regulated autophagy modulator 1
- DNA damage-regulated autophagy modulator protein 1
- damage-regulated autophagy modulator
- Damage-regulated autophagy modulator
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