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DRAM 产品

(DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

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This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008].

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Featured DRAM Categories

DRAM 抗体

High quality antibodies with extensive validation data.

DRAM ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended DRAM 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7150140
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6745422
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7266817
Quantity 100 μL
Datasheet Datasheet

Recommended DRAM ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966397
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6224930
Quantity 96 tests
Datasheet Datasheet

Recommended DRAM 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3129628
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3103309
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DRAM Products

Chen, Chen, Liu, Wang, Pan, Teng: "TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells." in: Cancer letters, Vol. 336, Issue 2, pp. 370-8, (2013) (PubMed).

Crighton, Wilkinson, Ryan: "DRAM links autophagy to p53 and programmed cell death." in: Autophagy, Vol. 3, Issue 1, pp. 72-4, (2007) (PubMed).

Crighton, Wilkinson, OPrey, Syed, Smith, Harrison, Gasco, Garrone, Crook, Ryan: "DRAM, a p53-induced modulator of autophagy, is critical for apoptosis." in: Cell, Vol. 126, Issue 1, pp. 121-34, (2006) (PubMed).

Gozuacik, Kimchi: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).

Synonyms and alternative names related to DRAM

DNA damage regulated autophagy modulator 1 (DRAM1), DNA-damage regulated autophagy modulator 1 (Dram1), DNA damage regulated autophagy modulator 1 L homeolog (dram1.L), 1200002N14Rik, DRAM, Dram, dram, DRAM1

Protein level used designations for DRAM

  • DNA-damage regulated autophagy modulator 1
  • DNA damage-regulated autophagy modulator protein 1
  • damage-regulated autophagy modulator
  • Damage-regulated autophagy modulator
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