DR4 产品
(Drought-Repressed 4 Protein (DR4))
Categories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008].
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DR4 抗体
High quality antibodies with extensive validation data.
Recommended DR4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN670581
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN3184356
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7214618
Quantity
100 μL
Datasheet
Datasheet
Recommended DR4 蛋白
Latest Publications for our DR4 Products
: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).: "cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter." in: Gene, Vol. 233, Issue 1-2, pp. 67-74, (1999) (PubMed).
: "An essential role for ectodomain shedding in mammalian development." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1281-4, (1998) (PubMed).
: "Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B." in: Current biology : CB, Vol. 6, Issue 12, pp. 1669-76, (1997) (PubMed).
: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).
Synonyms and alternative names related to DR4
TNF receptor superfamily member 10a (TNFRSF10A), APO2, CD261, DR4, TRAILR-1, TRAILR1Protein level used designations for DR4
- TNF-related apoptosis-inducing ligand receptor 1
- TRAIL receptor 1
- TRAIL-R1
- cytotoxic TRAIL receptor
- death receptor 4
- tumor necrosis factor receptor superfamily member 10A
- tumor necrosis factor receptor superfamily member 10a variant 2
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