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DOCK3 产品

(Dedicator of Cytokinesis 3 (DOCK3))
This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq, Aug 2010].

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Featured DOCK3 Categories

DOCK3 抗体

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DOCK3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended DOCK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7149587
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF (p), IHC (fro), IHC (p), ICC, IF (cc)
Validations
Cat. No. ABIN1387818
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7149590
Quantity 100 μg
Datasheet Datasheet

Recommended DOCK3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955298
Quantity 96 tests
Datasheet Datasheet

Recommended DOCK3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398815
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6378923
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to DOCK3

dedicator of cytokinesis 3 (DOCK3), similar to dedicator of cytokinesis 3 (LOC561387), dedicator of cytokinesis 3 (dock3), dedicator of cytokinesis protein 3 (LOC100474164), dedicator of cyto-kinesis 3 (Dock3), mKIAA0299, MOCA, PBP

Protein level used designations for DOCK3

  • dedicator of cytokinesis 3
  • similar to dedicator of cytokinesis 3
  • dedicator of cytokinesis protein 3-like
  • dedicator of cytokinesis protein 3
  • modifier of cell adhesion
  • presenilin-binding protein
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