DNMT3L 抗体
(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
recommended
recommended
TRDMT1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2D10H11 unconjugated
recommended
DNMT3L 抗体 by 适用
Find DNMT3L 抗体 for a variety of species such as anti-Human DNMT3L, anti-Mouse DNMT3L, anti-Rat DNMT3L. The species listed below are among those available. Click on a link to go to the corresponding products.
DNMT3L 抗体 by 抗体来源
Find DNMT3L 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
DNMT3L 抗体 by 克隆形成能力
Find available monoclonal or polyclonal DNMT3L 抗体. Click on a link to go to the corresponding products.
DNMT3L 抗体 by 克隆
Find DNMT3L 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
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Reactivity
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Validations
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Cat. No.
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Datasheet
Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IF, IP, ChIP, IC
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Cat. No.
ABIN7306130
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our DNMT3L 抗体
: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).: "DNA methyl transferases are differentially expressed in the human anterior eye segment." in: Acta ophthalmologica, Vol. 92, Issue 5, pp. e366-71, (2014) (PubMed).
: "An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism." in: PLoS ONE, Vol. 8, Issue 4, pp. e61758, (2013) (PubMed).
: "Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation." in: The EMBO journal, Vol. 26, Issue 8, pp. 2052-60, (2007) (PubMed).
: "Dnmt3L is a transcriptional repressor that recruits histone deacetylase." in: Nucleic acids research, Vol. 30, Issue 17, pp. 3831-8, (2002) (PubMed).
: "The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16916-21, (2002) (PubMed).
: "Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths." in: Molecular reproduction and development, Vol. 63, Issue 3, pp. 269-72, (2002) (PubMed).
: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ..." in: Nature, Vol. 420, Issue 6915, pp. 563-73, (2002) (PubMed).
: "Isolation and initial characterization of the mouse Dnmt3l gene." in: Cytogenetics and cell genetics, Vol. 92, Issue 1-2, pp. 122-6, (2001) (PubMed).
: "Dnmt3L and the establishment of maternal genomic imprints." in: Science (New York, N.Y.), Vol. 294, Issue 5551, pp. 2536-9, (2001) (PubMed).
Aliases for DNMT3L 抗体
DNA methyltransferase 3 like (DNMT3L) 抗体DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l) 抗体
DNA methyltransferase 3 like (Dnmt3l) 抗体
D6Ertd14e 抗体
DNMT3L 抗体
ecat7 抗体
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