DNMT3B 产品
(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011].
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Featured DNMT3B Categories
DNMT3B 抗体
High quality antibodies with extensive validation data.
DNMT3B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DNMT3B 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DNMT3B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, FACS
Validations
- (6)
Cat. No.
ABIN5542518
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, ICC
Validations
- (6)
Cat. No.
ABIN5542517
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN7203336
Quantity
100 μL
Datasheet
Datasheet
Recommended DNMT3B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955417
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955418
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690866
Quantity
96 tests
Datasheet
Datasheet
Recommended DNMT3B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1777739
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2719618
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409305
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DNMT3B Products
: "GADD45A binds R-loops and recruits TET1 to CpG island promoters." in: Nature genetics, Vol. 51, Issue 2, pp. 217-223, (2019) (PubMed).: "S-adenosylhomocysteine Hydrolase Participates in DNA Methylation Inheritance." in: Journal of molecular biology, Vol. 430, Issue 14, pp. 2051-2065, (2018) (PubMed).
: "Intragenic DNA methylation prevents spurious transcription initiation." in: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).
: "Testis specific Y-like 5: gene expression, methylation and implications for drug sensitivity in prostate carcinoma." in: BMC cancer, Vol. 17, Issue 1, pp. 158, (2017) (PubMed).
: "Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming." in: Scientific reports, Vol. 7, pp. 44667, (2017) (PubMed).
: "An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma." in: Oncotarget, Vol. 8, Issue 12, pp. 19712-19722, (2017) (PubMed).
: "Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway." in: The AAPS journal, Vol. 18, Issue 3, pp. 659-69, (2016) (PubMed).
: "Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 45, Issue 10, pp. 774-779, (2016) (PubMed).
: "Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood." in: Molecular neurobiology, (2016) (PubMed).
: "Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity." in: Cell reports, Vol. 16, Issue 7, pp. 1820-8, (2016) (PubMed).
Synonyms and alternative names related to DNMT3B
DNA methyltransferase 3 beta (DNMT3B), DNA methyltransferase 3 beta (Dnmt3b), DNA methyltransferase 3 beta (dnmt3b), DNA methyltransferase 3B (Dnmt3b), DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba), cb91, DNMT3B, dnmt3bl, dnmt7, ICF, ICF1, LOC100218113, M.HsaIIIB, MmuIIIB, sb:cb91, wu:fb16h07Protein level used designations for DNMT3B
- DNA cytosine-5 methyltransferase 3 beta
- DNA (cytosine-5)-methyltransferase 3B
- DNA methyltransferase HsaIIIB
- DNA (cytosine-5-)-methyltransferase 3 beta
- DNA MTase HsaIIIB
- DNA methyltransferase 3B
- DNA (cytosine-5)-methyltransferase 3B-like
- DNA MTase MmuIIIB
- DNA methyltransferase MmuIIIB
- DNA (cytosine-5-)-methyltransferase 3 beta, like
- DNA (cytosine-5-)-methyltransferase 7
- fb16h07
- LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B
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