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Dnmt2 产品

(tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

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This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010].

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Featured Dnmt2 Categories

Dnmt2 抗体

High quality antibodies with extensive validation data.

Dnmt2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Dnmt2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Dnmt2 抗体

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Cat. No. ABIN560633
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Cat. No. ABIN7173504
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Recommended Dnmt2 ELISA试剂盒

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Cat. No. ABIN4993419
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Reactivity Mouse
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Cat. No. ABIN1163942
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Recommended Dnmt2 蛋白

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Latest Publications for our Dnmt2 Products

Chen, Yang, Zhu, Yadav, Ouyang, Truesdell, Tan, Wang, Duan, Wei, Zou, Levine, Vasudevan, Lan: "m5C modification of mRNA serves a DNA damage code to promote homologous recombination." in: Nature communications, Vol. 11, Issue 1, pp. 2834, (2020) (PubMed).

Su, Zhang, Lee, Shu, Wu, Khor, Conney, Lu, Kong: "Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 3, pp. 319-29, (2014) (PubMed).

Lee, Jang, Benoit, Hoque, Califano, Trink, Sidransky, Mao, Moon: "Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome." in: Genomics, Vol. 96, Issue 2, pp. 67-72, (2010) (PubMed).

Wu, Alvarez, Slamon, Koeffler, Vadgama: "Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation." in: BMC cancer, Vol. 10, pp. 32, (2010) (PubMed).

Rai, Chidester, Zavala, Manos, James, Karpf, Jones, Cairns: "Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish." in: Genes & development, Vol. 21, Issue 3, pp. 261-6, (2007) (PubMed).

Kawasaki, Taira: "Induction of DNA methylation and gene silencing by short interfering RNAs in human cells." in: Nature, Vol. 431, Issue 7005, pp. 211-7, (2004) (PubMed).

Hermann, Schmitt, Jeltsch: "The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31717-21, (2003) (PubMed).

Dong, Yoder, Zhang, Zhou, Bestor, Cheng: "Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA." in: Nucleic acids research, Vol. 29, Issue 2, pp. 439-48, (2001) (PubMed).

Franchina, Hooper, Kay: "Five novel alternatively spliced transcripts of DNA (cytosine-5) methyltransferase 2 in human peripheral blood leukocytes." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 11, pp. 1104-15, (2001) (PubMed).

Synonyms and alternative names related to Dnmt2

tRNA aspartic acid methyltransferase 1 (trdmt1), tRNA aspartic acid methyltransferase 1 (TRDMT1), tRNA aspartic acid methyltransferase 1 (Trdmt1), tRNA aspartic acid methyltransferase 1 L homeolog (trdmt1.L), DMNT2, DNMT2, Dnmt2, dnmt2, MGC89267, MHSAIIP, PUMET, RNMT1, Rnmt2

Protein level used designations for Dnmt2

  • tRNA aspartic acid methyltransferase 1
  • DNA (cytosine-5)-methyltransferase-like protein 2
  • DNA MTase homolog HsaIIP
  • DNA methyltransferase-2
  • tRNA (cytosine(38)-C(5))-methyltransferase
  • tRNA (cytosine-5-)-methyltransferase
  • DNA MTase homolog MmuIIP
  • DNA methyltransferase 2
  • DNA methyltransferase homolog MmuIIP
  • m.MmuIIP
  • met-2
  • DNA (cytosine-5-)-methyltransferase 2
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