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Dnah5 抗体

(Dynein, Axonemal, Heavy Chain 5 (Dnah5))
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009].

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Dnah5 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our Dnah5 Products

Onoufriadis, Shoemark, Schmidts, Patel, Jimenez, Liu, Thomas, Dixon, Hirst, Rutman, Burgoyne, Williams, Scully, Bolard, Lafitte, Beales, Hogg, Yang, Chung, Emes, OCallaghan, Bouvagnet, Mitchison: "Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects." in: Human molecular genetics, Vol. 23, Issue 13, pp. 3362-74, (2014) (PubMed).

Diggle, Moore, Mali, zur Lage, Ait-Lounis, Schmidts, Shoemark, Garcia Munoz, Halachev, Gautier, Yeyati, Bonthron, Carr, Hayward, Markham, Hope, von Kriegsheim, Mitchison, Jackson, Durand, Reith et al.: "HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. ..." in: PLoS genetics, Vol. 10, Issue 9, pp. e1004577, (2014) (PubMed).

Onoufriadis, Shoemark, Munye, James, Schmidts, Patel, Rosser, Bacchelli, Beales, Scambler, Hart, Danke-Roelse, Sloper, Hull, Hogg, Emes, Pals, Moore, Chung, Mitchison: "Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm." in: Journal of medical genetics, Vol. 51, Issue 1, pp. 61-7, (2013) (PubMed).

Synonyms and alternative names related to Dnah5

dynein axonemal heavy chain 5 (DNAH5), dynein, axonemal, heavy chain 5 (DNAH5), dynein heavy chain 5, axonemal (LOC725479), dynein heavy chain 8, axonemal (LOC100182341), dynein heavy chain 5, axonemal (LOC100209217), dynein heavy chain 5, axonemal (LOC100389549), dynein axonemal heavy chain 5 S homeolog (dnah5.S), dynein heavy chain 8, axonemal (LOC100638612), dynein, axonemal, heavy chain 5 (Dnah5), AU022615, b2b601Clo, b2b1134Clo, b2b1154Clo, b2b1537Clo, b2b1565Clo, CILD3, DLP5, DNAHC5, Dnahc5, Dnahc8, HL1, KTGNR, Mdnah5, mKIAA1603, PCD

Protein level used designations for Dnah5

  • dynein, axonemal, heavy chain 5
  • dynein, axonemal, heavy polypeptide 5
  • dynein heavy chain 5, axonemal-like
  • axonemal beta dynein heavy chain 5
  • ciliary dynein heavy chain 5
  • dynein heavy chain 5, axonemal
  • axonemal dynein heavy chain 5
  • dynein, axon, heavy chain 5
  • dynein heavy chain
  • dynein-like protein 5
  • dynein-like prot ein 5
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