DMAP1 产品
(DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
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Featured DMAP1 Categories
DMAP1 抗体
High quality antibodies with extensive validation data.
DMAP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DMAP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DMAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN6139677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN565960
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7150197
Quantity
100 μg
Datasheet
Datasheet
Recommended DMAP1 ELISA试剂盒
Recommended DMAP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1351708
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092188
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137265
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DMAP1 Products
: "MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome." in: Gut, (2015) (PubMed).: "Novel 1p tumour suppressor Dnmt1-associated protein 1 regulates MYCN/ataxia telangiectasia mutated/p53 pathway." in: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 8, pp. 1555-65, (2014) (PubMed).
: "DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci." in: Nature genetics, Vol. 25, Issue 3, pp. 269-77, (2000) (PubMed).
Synonyms and alternative names related to DMAP1
DNA methyltransferase 1-associated protein DMAP1 (AFUA_4G07380), DNA methyltransferase 1-associated protein DMAP1 (NFIA_108840), DNA methyltransferase 1-associated protein DMAP1 (ACLA_046700), DNA methyltransferase 1-associated protein 1 (CpipJ_CPIJ017959), DNA methyltransferase 1 associated protein 1 (Bm1_47540), DNA methyltransferase 1-associated protein DMAP1 (PMAA_026820), DNA methyltransferase 1-associated protein DMAP1 (AFLA_112450), DNA methyltransferase 1-associated protein DMAP1 (TSTA_072020), DNA methyltransferase 1-associated protein DMAP1 (BDBG_02603), myb-like transcription factor family protein (AT2G47210), DNA methyltransferase 1-associated protein 1 (CpipJ_CPIJ007438), DNA methyltransferase 1 associated protein 1 (DMAP1), DNA methyltransferase 1 associated protein 1 (dmap1), DNA methyltransferase 1 associated protein 1 L homeolog (dmap1.L), DNA methyltransferase 1-associated protein 1 (Dmap1), 1500016M21Rik, Afu4g07380, Dmtap1, DNMAP1, dnmap1, DNMTAP1, dnmtap1, EAF2, eaf2, MEAF2, meaf2, mKIAA1425, SWC4, swc4, T8I13.5, zgc:55593Protein level used designations for DMAP1
- DNA methyltransferase 1-associated protein DMAP1
- DNA methyltransferase 1-associated protein 1
- DNA methyltransferase 1 associated protein 1
- DNMT1 associated protein 1
- DNMT1-associated protein 1
- DNMT1 associated protein-1
- MAT1-mediated transcriptional repressor
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