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DLL1 产品

(delta-Like 1 (DLL1))
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].

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Featured DLL1 Categories

DLL1 抗体

High quality antibodies with extensive validation data.

DLL1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DLL1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DLL1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, FACS, IF
Validations
  • (7)
Cat. No. ABIN361190
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (2)
  • (5)
Cat. No. ABIN2782684
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN129638
Quantity 100 μg
Datasheet Datasheet

Recommended DLL1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955337
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955338
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955339
Quantity 96 tests
Datasheet Datasheet

Recommended DLL1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274481
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7319919
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351685
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DLL1 Products

Tetzlaff, Adam, Feldner, Moll, Menuchin, Rodriguez-Vita, Sprinzak, Fischer: "MPDZ promotes DLL4-induced Notch signaling during angiogenesis." in: eLife, Vol. 7, (2018) (PubMed).

Marcel, Sarin: "Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells." in: eLife, Vol. 5, (2016) (PubMed).

DSouza, Zhou, Rebalka, MacDonald, Moradi, Krause, Al-Sajee, Punthakee, Tarnopolsky, Hawke: "Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling." in: Diabetes, Vol. 65, Issue 10, pp. 3053-61, (2016) (PubMed).

Hatakeyama, Wakamatsu, Nagafuchi, Kageyama, Shigemoto, Shimamura: "Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates." in: Development (Cambridge, England), Vol. 141, Issue 8, pp. 1671-82, (2014) (PubMed).

Lemke, von Karstedt, Abd El Hay, Conti, Arce, Montinaro, Papenfuss, El-Bahrawy, Walczak: "Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1." in: Cell death and differentiation, Vol. 21, Issue 3, pp. 491-502, (2014) (PubMed).

Caliceti, Aquila, Pannella, Morelli, Fortini, Pinton, Bonora, Hrelia, Pannuti, Miele, Rizzo, Ferrari: "17?-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71440, (2013) (PubMed).

Villaamil, Gallego, Valladares-Ayerbes, Caínzos, Aparicio: "Multiple biomarker tissue arrays: A computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway." in: Journal of molecular signaling, Vol. 7, Issue 1, pp. 14, (2012) (PubMed).

Suprynowicz, Upadhyay, Krawczyk, Kramer, Hebert, Liu, Yuan, Cheluvaraju, Clapp, Boucher, Kamonjoh, Randell, Schlegel: "Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20035-40, (2012) (PubMed).

Jenkins, Ross, Veldman-Jones, Foltz, Clavette, Manchulenko, Eberlein, Kendrew, Petteruti, Cho, Damschroder, Peng, Baker, Smith, Weir, Blakey, Bedian, Barry: "MEDI0639: a novel therapeutic antibody targeting Dll4 modulates endothelial cell function and angiogenesis in vivo." in: Molecular cancer therapeutics, Vol. 11, Issue 8, pp. 1650-60, (2012) (PubMed).

Le Friec, Sheppard, Whiteman, Karsten, Shamoun, Laing, Bugeon, Dallman, Melchionna, Chillakuri, Smith, Drouet, Couzi, Fremeaux-Bacchi, Köhl, Waddington, McDonnell, Baker, Handford, Lea, Kemper: "The CD46-Jagged1 interaction is critical for human TH1 immunity." in: Nature immunology, Vol. 13, Issue 12, pp. 1213-21, (2012) (PubMed).

Synonyms and alternative names related to DLL1

delta-like 1 (dll1), delta like canonical Notch ligand 1 (DLL1), delta like non-canonical Notch ligand 1 (DLK1), delta like canonical Notch ligand 1 (Dll1), delta-like 1 L homeolog (dll1.L), delta-like 1 (Drosophila) (Dll1), delta-like 1 homolog (Drosophila) (Dlk1), AW742678, delta, Delta, delta-1, delta1, DELTA1, Delta1, DL1, DLK, DLK-1, DlkI, DLL1, FA1, Ly107, Peg9, pG2, Pref-1, pref-1, PREF1, SCP1, x-delta, X-delta-1, Xdelta-1, XDelta1, ZOG

Protein level used designations for DLL1

  • H-Delta-1
  • delta-like protein 1
  • drosophila Delta homolog 1
  • fetal antigen 1
  • preadipocyte factor 1
  • protein delta homolog 1
  • secredeltin
  • delta1
  • delta-like 1 (Drosophila)
  • C-Delta-1
  • delta-like 1
  • x-Delta-1
  • delta like-1
  • adipocyte differentiation inhibitor protein
  • stromal cell derived protein 1
  • Delta-like protein 1
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