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DKK3 产品

(DKK3)

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This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

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Featured DKK3 Categories

DKK3 抗体

High quality antibodies with extensive validation data.

DKK3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended DKK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (6)
Cat. No. ABIN7443053
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (4)
Cat. No. ABIN1098142
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7260483
Quantity 200 μL
Datasheet Datasheet

Recommended DKK3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962873
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955413
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955414
Quantity 96 tests
Datasheet Datasheet

Recommended DKK3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274470
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274471
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351651
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DKK3 Products

Al-Dhohorah, Mashrah, Yao, Huang: "Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study." in: European journal of histochemistry : EJH, Vol. 60, Issue 2, pp. 2629, (2017) (PubMed).

Zhang, Du, Ling, Li, Liao, Wei: "Dickkopf-related protein 3 negatively regulates the osteogenic differentiation of rat dental follicle cells." in: Molecular medicine reports, Vol. 15, Issue 4, pp. 1673-1681, (2017) (PubMed).

Du, Kataoka, Sakaguchi, Abarzua, Than, Sonegawa, Makino, Shimizu, Huh: "Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis." in: Experimental dermatology, Vol. 20, Issue 3, pp. 273-7, (2011) (PubMed).

Medinger, Tzankov, Kern, Pircher, Hermann, Ott, Gastl, Untergasser, Gunsilius: "Increased Dkk3 protein expression in platelets and megakaryocytes of patients with myeloproliferative neoplasms." in: Thrombosis and haemostasis, Vol. 105, Issue 1, pp. 72-80, (2011) (PubMed).

Veeck, Bektas, Hartmann, Kristiansen, Heindrichs, Knüchel, Dahl: "Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours." in: Breast cancer research : BCR, Vol. 10, Issue 5, pp. R82, (2009) (PubMed).

Pei, Kano, Iijima, Morishita, Inadome, Noguchi: "Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).

Kuphal, Lodermeyer, Bataille, Schuierer, Hoang, Bosserhoff: "Expression of Dickkopf genes is strongly reduced in malignant melanoma." in: Oncogene, Vol. 25, Issue 36, pp. 5027-36, (2006) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Kurose, Sakaguchi, Nasu, Ebara, Kaku, Kariyama, Arao, Miyazaki, Tsushima, Namba, Kumon, Huh: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." in: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Synonyms and alternative names related to DKK3

dickkopf WNT signaling pathway inhibitor 3 (DKK3), dickkopf WNT signaling pathway inhibitor 3 (dkk3), dickkopf WNT signaling pathway inhibitor 3 S homeolog (dkk3.S), dickkopf WNT signaling pathway inhibitor 3 (Dkk3), AW061014, C87148, dkk-3, p29, REIC, reic, Reic, RIG

Protein level used designations for DKK3

  • RIG-like 5-6
  • RIG-like 7-1
  • dickkopf 3 homolog
  • dickkopf homolog 3
  • dickkopf-3
  • dickkopf-related protein 3
  • dkk-3
  • hDkk-3
  • regulated in glioma
  • dickkopf 3
  • mDkk-3
  • lens fiber protein CLFEST4
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