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DIS3L 产品

(DIS3-Like Exonuclease 1 (DIS3L))

Categories

Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

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Featured DIS3L Categories

DIS3L 抗体

High quality antibodies with extensive validation data.

DIS3L ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DIS3L 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DIS3L 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7150013
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN530352
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN530351
Quantity 50 μL
Datasheet Datasheet

Recommended DIS3L ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1129844
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129845
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1129846
Quantity 96 tests
Datasheet Datasheet

Recommended DIS3L 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351631
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092157
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136343
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DIS3L Products

Tomecki, Drazkowska, Kucinski, Stodus, Szczesny, Gruchota, Owczarek, Kalisiak, Dziembowski: "Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target." in: Nucleic acids research, Vol. 42, Issue 2, pp. 1270-90, (2014) (PubMed).

Staals, Bronkhorst, Schilders, Slomovic, Schuster, Heck, Raijmakers, Pruijn: "Dis3-like 1: a novel exoribonuclease associated with the human exosome." in: The EMBO journal, Vol. 29, Issue 14, pp. 2358-67, (2010) (PubMed).

Synonyms and alternative names related to DIS3L

DIS3 like exosome 3'-5' exoribonuclease (DIS3L), DIS3 like exosome 3'-5' exoribonuclease (dis3l), DIS3 like exosome 3'-5' exoribonuclease (Dis3l), DIS3-like exosome 3'-5' exoribonuclease (Dis3l), DIS3 like exosome 3'-5' exoribonuclease (dis3l.L), AV340375, DIS3L1, RGD1308959, zgc:158615

Protein level used designations for DIS3L

  • DIS3-like exonuclease 1
  • DIS3-like exonuclease 1-like
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