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DIS3 蛋白

(Exosome Complex Exonuclease RRP44 (DIS3))

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. DIS3 has both 3'-5' exonuclease and endonuclease activities (By similarity).

recommended

DIS3 Protein (AA 861-956) (GST tag) (ABIN1351629)

DIS3 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

DIS3 Protein (AA 1-958) (Strep Tag) (ABIN3095104)

DIS3 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

DIS3 Protein (AA 1-958) (Strep Tag) (ABIN3137036)

DIS3 宿主: 小鼠宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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DIS3 蛋白 by Origin

Find DIS3 蛋白 for a variety of species such as anti-Human DIS3, anti-Mouse DIS3. The species listed below are among those available. Click on a link to go to the corresponding products.

DIS3 蛋白 by Source

Here you will find DIS3 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DIS3 蛋白 by 蛋白类型

Here you can find DIS3 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

DIS3 蛋白 by 应用范围

Find DIS3 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DIS3 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

DIS3 Protein (AA 861-956) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351629

Quantity 10 μg

Datasheet Datasheet

DIS3 Protein (AA 1-958) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3095104

Quantity 1 mg

Datasheet Datasheet

DIS3 Protein (AA 1-958) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3137036

Quantity 1 mg

Datasheet Datasheet

DIS3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719499

Quantity 20 μg

Datasheet Datasheet

Aliases for DIS3 蛋白

DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease (DIS3) 蛋白
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease (Dis3) 蛋白
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease (dis3) 蛋白
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease (dis3.L) 蛋白
2810028N01Rik 蛋白
bA555G22.1 蛋白
DIS3 蛋白
dis3 蛋白
dis3p 蛋白
EXOSC11 蛋白
KIAA1008 蛋白
RGD1304646 蛋白
RP11-342J4.3 蛋白
RRP44 蛋白
wu:fb08g12 蛋白

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DIS3 蛋白 by Origin

DIS3 蛋白 by Source

DIS3 蛋白 by 蛋白类型

DIS3 蛋白 by 应用范围

Popular DIS3 蛋白

Aliases for DIS3 蛋白

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