DIO2 产品
(Deiodinase, Iodothyronine, Type II (DIO2))
Categories
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured DIO2 Categories
DIO2 抗体
High quality antibodies with extensive validation data.
DIO2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DIO2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DIO2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, FACS, IF
Validations
- (1)
- (3)
Cat. No.
ABIN190862
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (5)
Cat. No.
ABIN652664
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7173972
Quantity
100 μg
Datasheet
Datasheet
Recommended DIO2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6966307
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955327
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955328
Quantity
96 tests
Datasheet
Datasheet
Recommended DIO2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351608
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413544
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413547
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DIO2 Products
: "Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice." in: The Science of the total environment, Vol. 668, pp. 310-317, (2019) (PubMed).: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." in: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).
: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." in: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).
: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).
: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." in: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).
: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." in: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).
Synonyms and alternative names related to DIO2
iodothyronine deiodinase 2 (DIO2), deiodinase, iodothyronine, type II (Dio2), iodothyronine deiodinase 2 (dio2), deiodinase, iodothyronine, type II (dio2), deiodinase, iodothyronine, type 2 L homeolog (dio2.L), deiodinase, iodothyronine, type 2 (dio2), iodothyronine deiodinase 2 (Dio2), type II iodothyronine deiodinase (LOC100861220), 5DII, 5dii, AI324267, cb684, D2, Deio2, DIO2, dio2-A, DIOII, SelY, sely, TXDI2, txdi2Protein level used designations for DIO2
- thyroxine deiodinase, type II
- type 2 DI
- type 2 iodothyronine deiodinase
- type II iodothyronine deiodinase
- type-II 5'-deiodinase
- type-II 5'deiodinase
- iodothyronine type II deiodinase
- type-II 5' deiodinase
- deiodinase, iodothyronine, type 2
- D2
- 5DII
- DIOII
- deiodinase, iodothyronine, type II
- deiodinase 2
- type 2 deiodinase
You are here:
