DFFA 抗体
(DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
DFFA 抗体 by 适用
Find DFFA 抗体 for a variety of species such as anti-Human DFFA, anti-Mouse DFFA, anti-Rat DFFA. The species listed below are among those available. Click on a link to go to the corresponding products.
DFFA 抗体 by 抗体来源
Find DFFA 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
DFFA 抗体 by 克隆形成能力
Find available monoclonal or polyclonal DFFA 抗体. Click on a link to go to the corresponding products.
DFFA 抗体 by 克隆
Find DFFA 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular DFFA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
Cat. No.
ABIN514954
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (4)
Cat. No.
ABIN7150176
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7442849
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (4)
Cat. No.
ABIN514956
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN514953
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN461876
Quantity
0.05 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193432
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC
Validations
- (5)
Cat. No.
ABIN5013466
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1498772
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6261279
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN6139548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP, IC
Validations
- (3)
Cat. No.
ABIN7295492
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN2719431
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (1)
Cat. No.
ABIN726380
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN203383
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our DFFA 抗体
: "Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression." in: Oncogene, Vol. 21, Issue 15, pp. 2283-94, (2002) (PubMed).: "Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49504-10, (2002) (PubMed).
: "Solution structure of the DFF-C domain of DFF45/ICAD. A structural basis for the regulation of apoptotic DNA fragmentation." in: Journal of molecular biology, Vol. 321, Issue 2, pp. 317-27, (2002) (PubMed).
: "Growth phase-dependent expression of ICAD-L/DFF45 modulates the pattern of apoptosis in human colonic cancer cells." in: Cancer research, Vol. 62, Issue 7, pp. 2169-74, (2002) (PubMed).
: "The regulation of DNAse activities in subcellular compartments of activated thymocytes." in: Immunology, Vol. 105, Issue 4, pp. 399-406, (2002) (PubMed).
: "Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 41, pp. 38185-92, (2001) (PubMed).
: "Functional differences of two forms of the inhibitor of caspase-activated DNase, ICAD-L, and ICAD-S." in: The Journal of biological chemistry, Vol. 274, Issue 22, pp. 15740-4, (1999) (PubMed).
: "Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40." in: The Journal of biological chemistry, Vol. 274, Issue 30, pp. 20759-62, (1999) (PubMed).
: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." in: Nature, Vol. 391, Issue 6662, pp. 43-50, (1998) (PubMed).
: "Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis." in: Nature, Vol. 391, Issue 6662, pp. 96-9, (1998) (PubMed).
Aliases for DFFA 抗体
DNA fragmentation factor subunit alpha (DFFA) 抗体DNA fragmentation factor, alpha subunit (Dffa) 抗体
DNA fragmentation factor, 45kDa, alpha polypeptide (dffa) 抗体
DNA fragmentation factor subunit alpha (Dffa) 抗体
DNA fragmentation factor, alpha polypeptide (dffa) 抗体
A330085O09Rik 抗体
DFF-45 抗体
DFF1 抗体
DFF35 抗体
Dff45 抗体
DFFA 抗体
ICAD 抗体
ICAD-L 抗体
ICAD-S 抗体
zgc:92229 抗体
您还需要查找其他产品吗？
- DEXI 抗体
- Developmental Pluripotency Associated 4 抗体
- Developing Brain Homeobox 1 抗体
- DET1 抗体
- Destrin 抗体
- Desmoplakin 抗体
- Desmoglein 4 抗体
- Desmoglein 3 抗体
- Desmoglein 2 抗体
- Desmoglein 1 抗体
- Desmocollin 3 抗体
- Desmocollin 2 抗体
- Desmocollin 1 抗体
- Desmin 抗体
- DESI1 抗体
- desert Hedgehog 抗体
- Dermokine 抗体
- Dermcidin 抗体
- Dermatopontin 抗体
- Derlin-3 抗体
You are here:
