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desert Hedgehog 产品

(Desert Hedgehog (DHH))

Categories

This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010].

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Featured desert Hedgehog Categories

desert Hedgehog 抗体

High quality antibodies with extensive validation data.

desert Hedgehog ELISA试剂盒

Reliable ELISA kits for a wide range of species.

desert Hedgehog 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended desert Hedgehog 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7438166
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7437344
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7190469
Quantity 100 μL
Datasheet Datasheet

Recommended desert Hedgehog ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955358
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6974699
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966339
Quantity 96 tests
Datasheet Datasheet

Recommended desert Hedgehog 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5509480
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667084
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122645
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our desert Hedgehog Products

Wellbrock, Latuske, Köhler, Wagner, Stamm, Vettorazzi, Vohwinkel, Klokow, Uibeleisen, Ehm, Riecken, Loges, Thol, Schubert, Amling, Jücker, Bokemeyer, Heuser, Krauter, Fiedler: "Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2388-98, (2016) (PubMed).

Bashir, Halepoto, Al-Ayadhi: "Serum level of desert hedgehog protein in autism spectrum disorder: preliminary results." in: Medical principles and practice : international journal of the Kuwait University, Health Science Centre, Vol. 23, Issue 1, pp. 14-7, (2014) (PubMed).

Callier, Calvel, Matevossian, Makrythanasis, Bernard, Kurosaka, Vannier, Thauvin-Robinet, Borel, Mazaud-Guittot, Rolland, Desdoits-Lethimonier, Guipponi, Zimmermann, Stévant, Kuhne, Conne, Santoni et al.: "Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling. ..." in: PLoS genetics, Vol. 10, Issue 5, pp. e1004340, (2014) (PubMed).

McKee, Xu, Cao, Kabraji, Allen, Kersemans, Beech, Smart, Hamdy, Ishkanian, Sykes, Pintile, Milosevic, van der Kwast, Zafarana, Ramnarine, Jurisica, Mallof, Lam, Bristow, Muschel: "Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma." in: The Journal of clinical investigation, Vol. 122, Issue 11, pp. 4025-36, (2012) (PubMed).

Nishimori, Ehata, Suzuki, Katsuno, Miyazono: "Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals." in: The Journal of biological chemistry, Vol. 287, Issue 24, pp. 20037-46, (2012) (PubMed).

Synonyms and alternative names related to desert Hedgehog

desert hedgehog (DHH), desert hedgehog (dhh), desert hedgehog (Dhh), desert hedgehog L homeolog (dhh.L), desert hedgehog S homeolog (dhh.S), C78960, chh, chh-a, dhh, dhh-1, dhh-A, GDXYM, hh4, HHG-3, SRXY7, x-chh, Xchh

Protein level used designations for desert Hedgehog

  • desert hedgehog homolog
  • desert hedgehog protein
  • mutant desert hedgehog
  • HHG-3
  • desert hedgehog
  • DHH-1
  • X-CHH
  • cephalic hedgehog protein
  • desert hedgehog protein 1
  • desert hedgehog protein A
  • DHH-2
  • X-HH4
  • cephalic hedgehog
  • desert hedgehog homolog, hedgehog protein 4
  • desert hedgehog protein 2
  • desert hedgehog protein B
  • hedgehog protein 4
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