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Deoxyuridine Triphosphatase 抗体

(Deoxyuridine Triphosphatase (DUT))
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq, Jul 2008].
Deoxyuridine Triphosphatase (DUT) (AA 68-164) 抗体 Deoxyuridine Triphosphatase (DUT) (AA 68-164) 抗体 Deoxyuridine Triphosphatase (DUT) (AA 68-164) 抗体 (ABIN560672)

DUT 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1C9 unconjugated

Deoxyuridine Triphosphatase (DUT) 抗体 Deoxyuridine Triphosphatase (DUT) 抗体 Deoxyuridine Triphosphatase (DUT) 抗体 (ABIN7260715)

DUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Deoxyuridine Triphosphatase (DUT) (AA 89-252) 抗体 Deoxyuridine Triphosphatase (DUT) (AA 89-252) 抗体 Deoxyuridine Triphosphatase (DUT) (AA 89-252) 抗体 (ABIN7266736)

DUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Deoxyuridine Triphosphatase 抗体 by Grade

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Deoxyuridine Triphosphatase 抗体 by 适用

Find Deoxyuridine Triphosphatase 抗体 for a variety of species such as anti-Human Deoxyuridine Triphosphatase, anti-Mouse Deoxyuridine Triphosphatase, anti-Rat Deoxyuridine Triphosphatase. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Deoxyuridine Triphosphatase 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Deoxyuridine Triphosphatase 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (1)
  • (5)
Cat. No. ABIN560672
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7260715
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7266736
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN5539501
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN629626
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN733478
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7237970
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN515114
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN321010
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN630705
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN2782437
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5534888
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN718436
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN947813
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN232967
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our Deoxyuridine Triphosphatase 抗体

Kiyonari, Iimori, Matsuoka, Watanabe, Morikawa-Ichinose, Miura, Niimi, Saeki, Tokunaga, Oki, Morita, Kadomatsu, Maehara, Kitao: "The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis." in: Molecular cancer therapeutics, Vol. 14, Issue 10, pp. 2332-42, (2015) (PubMed).

Tóth, Varga, Kovács, Málnási-Csizmadia, Vértessy: "Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33572-82, (2007) (PubMed).

Studebaker, Lafuse, Kloesel, Williams: "Modulation of human dUTPase using small interfering RNA." in: Biochemical and biophysical research communications, Vol. 327, Issue 1, pp. 306-10, (2005) (PubMed).

Ladner: "The role of dUTPase and uracil-DNA repair in cancer chemotherapy." in: Current protein & peptide science, Vol. 2, Issue 4, pp. 361-70, (2002) (PubMed).

Aliases for Deoxyuridine Triphosphatase 抗体

deoxyuridine triphosphatase (DUT) 抗体
Deoxyuridine triphosphatase (dUTPase) 抗体
deoxyuridine triphosphatase (P18) 抗体
dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 (AlHV1gp51) 抗体
deoxyuridine triphosphatase (UL50) 抗体
deoxyuridine triphosphatase (HVT058) 抗体
involved in nucleotide metabolism (UL50) 抗体
deoxyuridine triphosphatase (ORF9) 抗体
deoxyuridine triphosphatase (ORF8) 抗体
tegument protein (U45) 抗体
dUTPase (GAMMAHV.ORF54) 抗体
deoxyuridine triphosphatase (Tc00.1047053509151.130) 抗体
deoxyuridine triphosphatase (Tc00.1047053508175.160) 抗体
deoxyuridine triphosphatase (Tb927.7.5160) 抗体
deoxyuridine triphosphatase L homeolog (dut.L) 抗体
deoxyuridine triphosphatase (Dut) 抗体
5031412I06Rik 抗体
5133400F09Rik 抗体
anon-SAGE:Wang-077 抗体
BcDNA:LD08534 抗体
CG4584 抗体
D2Bwg0749e 抗体
Dmel\\CG4584 抗体
Dutp 抗体
dUTPase 抗体
dutpase 抗体
LD08534 抗体
PIP4 抗体
Tb07.27E10.390 抗体
UTPase 抗体
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