DEK 产品
(DEK Oncogene (DEK))
Categories
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Featured DEK Categories
DEK 抗体
High quality antibodies with extensive validation data.
DEK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DEK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DEK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7266724
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6261268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN653133
Quantity
400 μL
Datasheet
Datasheet
Recommended DEK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974951
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1150831
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5591964
Quantity
96 tests
Datasheet
Datasheet
Recommended DEK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719372
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our DEK Products
: "Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma." in: Translational oncology, Vol. 11, Issue 1, pp. 168-174, (2018) (PubMed).: "Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence." in: PLoS genetics, Vol. 14, Issue 3, pp. e1007227, (2018) (PubMed).
: "Roles of DEK in the endometrium of mice in early pregnancy." in: Gene, Vol. 642, pp. 261-267, (2017) (PubMed).
: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." in: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).
: "The human DEK oncogene stimulates ?-catenin signaling, invasion and mammosphere formation in breast cancer." in: Oncogene, Vol. 30, Issue 24, pp. 2741-52, (2011) (PubMed).
: "Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer." in: BMC cancer, Vol. 11, pp. 234, (2011) (PubMed).
: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).
: "Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins." in: Journal of cellular biochemistry, Vol. 105, Issue 1, pp. 81-8, (2008) (PubMed).
: "DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 5, pp. 1811-5, (1997) (PubMed).
: "Purification of the pets factor. A nuclear protein that binds to the inducible TG-rich element of the human immunodeficiency virus type 2 enhancer." in: The Journal of biological chemistry, Vol. 271, Issue 32, pp. 19599-605, (1996) (PubMed).
Synonyms and alternative names related to DEK
DEK proto-oncogene (DEK), DEK proto-oncogene (Dek), DEK proto-oncogene L homeolog (dek.L), DEK oncogene (DNA binding) (Dek), DEK oncogene (LOC398543), 1810019E15Rik, D6S231E, D13H6S231E, DEKProtein level used designations for DEK
- DEK oncogene (DNA binding)
- protein DEK
- DEK oncogene
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