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Daf-2 抗体 (C-Term)

DAF2 适用: C. elegans IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965970
发货至: 中国
  • 抗原 See all Daf-2 (DAF2) products
    Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
    抗原表位
    C-Term
    适用
    C. elegans
    宿主
    克隆类型
    多克隆
    应用范围
    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
    别名
    Daf-2
    别名
    AI323748 antibody, Cd55b antibody, Daf antibody, Daf-TM antibody, TM-DAF antibody, CD55 molecule, decay accelerating factor for complement B antibody, Insulin-like receptor subunit beta antibody, Cd55b antibody, daf-2 antibody
    背景
    The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
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