DDIT3 产品
(DNA-Damage-Inducible Transcript 3 (DDIT3))
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This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010].
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Featured DDIT3 Categories
DDIT3 抗体
High quality antibodies with extensive validation data.
DDIT3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DDIT3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DDIT3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
- (6)
Cat. No.
ABIN3020710
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7437662
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
- (4)
Cat. No.
ABIN6260816
Quantity
100 μL
Datasheet
Datasheet
Recommended DDIT3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966399
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955427
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955428
Quantity
96 tests
Datasheet
Datasheet
Recommended DDIT3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351276
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351278
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351280
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our DDIT3 Products
: "Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 8976, (2019) (PubMed).: "Autophagy May Protect Against Parenteral Nutrition-Associated Liver Disease by Suppressing Endoplasmic Reticulum Stress." in: JPEN. Journal of parenteral and enteral nutrition, Vol. 43, Issue 1, pp. 96-106, (2019) (PubMed).
: "Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane." in: Molecular and cellular endocrinology, Vol. 480, pp. 36-41, (2019) (PubMed).
: "FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex." in: EMBO reports, Vol. 20, Issue 5, (2019) (PubMed).
: "A FBN1 3'UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 1, pp. 107-114, (2019) (PubMed).
: "Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice." in: Brain, behavior, and immunity, Vol. 79, pp. 284-293, (2019) (PubMed).
: "Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers." in: JCI insight, Vol. 4, Issue 9, (2019) (PubMed).
: "Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).
: "Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells." in: Biological research, Vol. 52, Issue 1, pp. 34, (2019) (PubMed).
: "A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus." in: Molecular neurobiology, (2019) (PubMed).
Synonyms and alternative names related to DDIT3
DNA damage inducible transcript 3 (ddit3), DNA-damage inducible transcript 3 (Ddit3), DNA damage inducible transcript 3 (DDIT3), DNA damage inducible transcript 3 L homeolog (ddit3.L), DNA damage inducible transcript 3 (Ddit3), cebpz, CEBPZ, chop, CHOP, CHOP-10, chop10, CHOP10, Chop10, gadd153, Gadd153, GADD153, XchopProtein level used designations for DDIT3
- C/EBP homoologous protein 10
- C/EBP zeta
- CCAAT/enhancer-binding protein homologous protein
- DDIT-3
- DNA damage-inducible transcript 3 protein
- c/EBP-homologous protein 10
- growth arrest and DNA-damage-inducible protein GADD153
- C/EBP homologous protein
- growth arrest and DNA damage-inducible protein GADD153
- growth arrest and DNA damage-inducible
- transcription factor GADD153
- C/EBP-homologous protein 10
- DNA-damage inducible transcript 3
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