(Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq, Jul 2008].
Find DDB2 ELISA试剂盒 for a variety of species such as anti-Chicken DDB2, anti-Cow DDB2, anti-Human DDB2. The species listed below are among those available. Click on a link to go to the corresponding products.
DDB2 ELISA试剂盒 by 检测方法
Find DDB2 ELISA试剂盒 with a specific 检测方法. The 检测方法 listed below are among those available. Click on a link to go to the corresponding products.
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