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DDB1 蛋白

(Damage Specific DNA Binding Protein 1 (DDB1))

The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012].

recommended

DDB1 Protein (AA 1-1140) (GST tag) (ABIN1351255)

DDB1 宿主: 人宿主: 小麦胚 Recombinant AA, AP, ELISA, WB

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recommended

DDB1 Protein (AA 1044-1140) (GST tag) (ABIN1351257)

DDB1 宿主: 人宿主: 小麦胚 Recombinant AA, AP, ELISA, WB

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DDB1 蛋白 by Origin

Find DDB1 蛋白 for a variety of species such as anti-Human DDB1. The species listed below are among those available. Click on a link to go to the corresponding products.

DDB1 蛋白 by Source

Here you will find DDB1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DDB1 蛋白 by 蛋白类型

Here you can find DDB1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

DDB1 蛋白 by 应用范围

Find DDB1 蛋白 validated for a specific application such as AP, AA, ELISA, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DDB1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

DDB1 Protein (AA 1-1140) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351255

Quantity 10 μg

Datasheet Datasheet

DDB1 Protein (AA 1044-1140) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351257

Quantity 10 μg

Datasheet Datasheet

Aliases for DDB1 蛋白

damage specific DNA binding protein 1 (DDB1) 蛋白
damage-specific DNA binding protein 1, 127kDa (ddb1) 蛋白
DNA damage-binding protein 1 (LOC100187356) 蛋白
damage specific DNA binding protein 1 (Ddb1) 蛋白
damage-specific DNA binding protein 1 (Ddb1) 蛋白
DNA damage-binding protein 1 (ddb-1) 蛋白
127kDa 蛋白
AA408517 蛋白
DDB1 蛋白
ddb1 蛋白
DDBA 蛋白
ddba 蛋白
p127-Ddb1 蛋白
UV-DDB1 蛋白
uv-ddb1 蛋白
XAP1 蛋白
xap1 蛋白
XPCE 蛋白
xpce 蛋白
XPE 蛋白
xpe 蛋白
XPE-BF 蛋白
xpe-bf 蛋白

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DDB1 蛋白 by Origin

DDB1 蛋白 by Source

DDB1 蛋白 by 蛋白类型

DDB1 蛋白 by 应用范围

Popular DDB1 蛋白

Aliases for DDB1 蛋白

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