DCK 产品
(Deoxycytidine Kinase (DCK))
Categories
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
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Featured DCK Categories
DCK 抗体
High quality antibodies with extensive validation data.
DCK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DCK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DCK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (7)
Cat. No.
ABIN1497773
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), FACS
Validations
- (9)
Cat. No.
ABIN1497775
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IP, IHC (p), ICC
Validations
- (6)
Cat. No.
ABIN2856517
Quantity
100 μL
Datasheet
Datasheet
Recommended DCK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966319
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955345
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1129460
Quantity
96 tests
Datasheet
Datasheet
Recommended DCK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667827
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351188
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396364
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DCK Products
: "Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity." in: BMC cancer, Vol. 18, Issue 1, pp. 466, (2018) (PubMed).: "Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer." in: Acta oncologica (Stockholm, Sweden), Vol. 55, Issue 3, pp. 286-96, (2016) (PubMed).
: "The effects of forodesine in murine and human multiple myeloma cells." in: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).
: "Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity." in: Blood, Vol. 113, Issue 10, pp. 2145-53, (2009) (PubMed).
: "The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase." in: Cancer research, Vol. 69, Issue 11, pp. 4567-72, (2009) (PubMed).
: "Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 7, pp. 773-84, (2008) (PubMed).
: "Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 323, Issue 3, pp. 935-45, (2007) (PubMed).
: "Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells." in: Molecular and cellular biochemistry, Vol. 231, Issue 1-2, pp. 173-7, (2002) (PubMed).
Synonyms and alternative names related to DCK
deoxycytidine kinase (DCK), deoxycytidine kinase (dck), deoxycytidine kinase, gene 2 L homeolog (dck.2.L), deoxycytidine kinase, gene 2 (dck.2), deoxycytidine kinase (Dck), Deoxycytidine kinase (FPV059), Deoxycytidine kinase (FPV151), deoxycytidine kinase, gene 1 L homeolog (dck.1.L), dck, DCK, dck1, wu:fc15f06, zgc:101771Protein level used designations for DCK
- deoxynucleoside kinase
- Deoxycytidine kinase
- deoxycytidine kinase
- deoxycytidine kinase 1
- deoxyribonucleoside kinase
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