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DCDC2 产品

(Doublecortin Domain Containing 2 (DCDC2))

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This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013].

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Featured DCDC2 Categories

DCDC2 抗体

High quality antibodies with extensive validation data.

DCDC2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Cat. No. ABIN7456335
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Cat. No. ABIN185538
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Cat. No. ABIN1385734
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Recommended DCDC2 蛋白

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Latest Publications for our DCDC2 Products

Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

Jeruschke, Jeruschke, DiStasio, Karaterzi, Büscher, Nalbant, Klein-Hitpass, Hoyer, Weiss, Stottmann, Weber: "Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137043, (2015) (PubMed).

McGrath, Smith, Pennington: "Breakthroughs in the search for dyslexia candidate genes." in: Trends in molecular medicine, Vol. 12, Issue 7, pp. 333-41, (2006) (PubMed).

Cope, Harold, Hill, Moskvina, Stevenson, Holmans, Owen, ODonovan, Williams: "Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia." in: American journal of human genetics, Vol. 76, Issue 4, pp. 581-91, (2005) (PubMed).

Synonyms and alternative names related to DCDC2

doublecortin domain containing 2 (DCDC2), doublecortin domain containing 2 (Dcdc2), doublecortin domain containing 2B (dcdc2b), DCDC2, DCDC2A, RU2, RU2S, zgc:123267

Protein level used designations for DCDC2

  • doublecortin domain-containing protein 2
  • doublecortin domain containing 2
  • doublecortin domain-containing protein 2-like
  • LOW QUALITY PROTEIN: doublecortin domain-containing protein 2
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