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DARS2 产品

(Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

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The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009].

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Featured DARS2 Categories

DARS2 抗体

High quality antibodies with extensive validation data.

DARS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DARS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6139409
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN949420
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (3)
Cat. No. ABIN7263833
Quantity 200 μL
Datasheet Datasheet

Recommended DARS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6201819
Quantity 96 tests
Datasheet Datasheet

Recommended DARS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351119
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421056
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422181
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DARS2 Products

Scheper, van der Klok, van Andel, van Berkel, Sissler, Smet, Muravina, Serkov, Uziel, Bugiani, Schiffmann, Krägeloh-Mann, Smeitink, Florentz, Van Coster, Pronk, van der Knaap: "Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation." in: Nature genetics, Vol. 39, Issue 4, pp. 534-9, (2007) (PubMed).

Bonnefond, Fender, Rudinger-Thirion, Giegé, Florentz, Sissler: "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS." in: Biochemistry, Vol. 44, Issue 12, pp. 4805-16, (2005) (PubMed).

Synonyms and alternative names related to DARS2

aspartyl-tRNA synthetase 2, mitochondrial (DARS2), aspartyl-tRNA synthetase 2, mitochondrial (dars2), aspartate--tRNA ligase, mitochondrial (LOC100547893), aspartyl-tRNA synthetase 2 (mitochondrial) (Dars2), 5830468K18Rik, ASPRS, LBSL, MT-ASPRS, RGD1308286, RP3-383J4.2, si:dkey-21n10.1

Protein level used designations for DARS2

  • aspartyl-tRNA synthetase 2, mitochondrial
  • aspartyl-tRNA synthetase 2 (mitochondrial)
  • aspartyl-tRNA synthetase, mitochondrial
  • aspartyl-tRNA synthetase, mitochondrial-like
  • aspRS
  • aspartate--tRNA ligase, mitochondrial
  • aspartate tRNA ligase 2, mitochondrial
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