DAAM1 抗体
(Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012].
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DAAM1 抗体 by 应用范围
Find DAAM1 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.
DAAM1 抗体 by 抗体来源
Find DAAM1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
DAAM1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal DAAM1 抗体. Click on a link to go to the corresponding products.
DAAM1 抗体 by 克隆
Find DAAM1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
DAAM1 抗体 by 标记
Find DAAM1 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular DAAM1 抗体
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Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
100 μg
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Cat. No.
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Quantity
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Datasheet
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Application
WB, IHC, ELISA
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Cat. No.
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Quantity
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Application
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Cat. No.
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Quantity
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Application
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Quantity
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Datasheet
Datasheet
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Application
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Bat, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
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Quantity
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Application
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Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
ABIN357855
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN357856
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA, IF, IP
Validations
Cat. No.
ABIN7113525
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
Cat. No.
ABIN4901374
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA, IF
Validations
Cat. No.
ABIN7132963
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Hamster, Human
Application
WB, IHC, FACS, IHC (p)
Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our DAAM1 抗体
: "DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility." in: The Journal of cell biology, Vol. 215, Issue 4, pp. 559-573, (2017) (PubMed).: "DAAM is required for thin filament formation and Sarcomerogenesis during muscle development in Drosophila." in: PLoS genetics, Vol. 10, Issue 2, pp. e1004166, (2014) (PubMed).
: "Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in wound healing." in: American journal of physiology. Cell physiology, Vol. 295, Issue 5, pp. C1215-29, (2008) (PubMed).
: "Mechanism of activation of the Formin protein Daam1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 210-5, (2008) (PubMed).
: "Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 16, pp. 6708-13, (2007) (PubMed).
: "Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly." in: Journal of molecular biology, Vol. 369, Issue 5, pp. 1258-69, (2007) (PubMed).
: "Crystal structure of human DAAM1 formin homology 2 domain." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 12, Issue 11, pp. 1255-65, (2007) (PubMed).
Aliases for DAAM1 抗体
dishevelled associated activator of morphogenesis 1 (DAAM1) 抗体dishevelled associated activator of morphogenesis 1 (Daam1) 抗体
dishevelled associated activator of morphogenesis 1 S homeolog (daam1.S) 抗体
dishevelled associated activator of morphogenesis 1a (daam1a) 抗体
dishevelled associated activator of morphogenesis 1 (daam1) 抗体
dishevelled associated activator of morphogenesis 1b (daam1b) 抗体
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