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CYP2F2 蛋白

(Cytochrome P450, Family 2, Subfamily F, Polypeptide 2 (CYP2F2))
Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl- 1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases. It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or Clara cells in lung.

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Synonyms and alternative names related to CYP2F2

cytochrome P450, family 2, subfamily f, polypeptide 2 (Cyp2f2), Cyp2f

Protein level used designations for CYP2F2

  • CYPIIF2
  • cytochrome P450 2F2
  • cytochrome P450, 2f2
  • cytochrome P450-NAH-2
  • naphthalene dehydrogenase
  • naphthalene hydroxylase
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