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CYP2C19 产品

(Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].

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Featured CYP2C19 Categories

CYP2C19 抗体

High quality antibodies with extensive validation data.

CYP2C19 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CYP2C19 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP2C19 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7149243
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN652231
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2777003
Quantity 100 μL
Datasheet Datasheet

Recommended CYP2C19 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955245
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966237
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648176
Quantity 96 tests
Datasheet Datasheet

Recommended CYP2C19 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3078371
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712765
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our CYP2C19 Products

Ji, Olson, Zhang, Hildebrandt, Wang, Ingle, Fredericksen, Sellers, Miller, Dixon, Brauch, Eichelbaum, Justenhoven, Hamann, Ko, Brüning, Chang-Claude, Wang-Gohrke, Schaid, Weinshilboum: "Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms." in: Cancer research, Vol. 68, Issue 14, pp. 5997-6005, (2008) (PubMed).

Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).

Synonyms and alternative names related to CYP2C19

cytochrome P450 family 2 subfamily C member 19 (CYP2C19), cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19), cytochrome P450 2C19 (CYP2C19), CPCJ, CYP2C, P450C2C, P450IIC19

Protein level used designations for CYP2C19

  • (R)-limonene 6-monooxygenase
  • (S)-limonene 6-monooxygenase
  • (S)-limonene 7-monooxygenase
  • CYPIIC17
  • CYPIIC19
  • S-mephenytoin 4-hydroxylase
  • cytochrome P-450 II C
  • cytochrome P450 2C19
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19
  • cytochrome P450-11A
  • cytochrome P450-254C
  • flavoprotein-linked monooxygenase
  • mephenytoin 4'-hydroxylase
  • mephenytoin 4-hydroxylase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
  • cytochrome P450 2C
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