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CYP2A6 抗体

(Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3\; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008].
CYP2A6 抗体 CYP2A6 抗体 CYP2A6 抗体 (ABIN1497724)

CYP2A6 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1D2 unconjugated

CYP2A6 抗体 CYP2A6 抗体 CYP2A6 抗体 (ABIN1497722)

CYP2A6 适用: 人 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2A8 unconjugated

CYP2A6 抗体 CYP2A6 抗体 CYP2A6 抗体 (ABIN1497723)

CYP2A6 适用: 人 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated

CYP2A6 抗体 by 适用

Find CYP2A6 抗体 for a variety of species such as anti-Human CYP2A6, anti-Rat CYP2A6, anti-Mouse CYP2A6. The species listed below are among those available. Click on a link to go to the corresponding products.

CYP2A6 抗体 by 应用范围

Find CYP2A6 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find CYP2A6 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

CYP2A6 抗体 by 抗原表位

Find CYP2A6 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CYP2A6 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CYP2A6 抗体. Click on a link to go to the corresponding products.

CYP2A6 抗体 by 克隆

Find CYP2A6 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

CYP2A6 抗体 by 标记

Find CYP2A6 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CYP2A6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, FACS, IHC (p)
Validations
  • (10)
Cat. No. ABIN1497724
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN1497722
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN1497723
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN514822
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN307110
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN514823
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN514824
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258062
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
Cat. No. ABIN7188680
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7184442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7149234
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7258314
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2855614
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN929448
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1944821
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP2A6 抗体

Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

Wang, Bian, Liu, Jin, Chen, Lin, Chen: "Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes." in: Pharmacogenomics, Vol. 12, Issue 4, pp. 481-92, (2011) (PubMed).

Higashi, Nakajima, Katoh, Tokudome, Yokoi: "Inhibitory effects of neurotransmitters and steroids on human CYP2A6." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 35, Issue 4, pp. 508-14, (2007) (PubMed).

Audrain-McGovern, Al Koudsi, Rodriguez, Wileyto, Shields, Tyndale: "The role of CYP2A6 in the emergence of nicotine dependence in adolescents." in: Pediatrics, Vol. 119, Issue 1, pp. e264-74, (2007) (PubMed).

Swan, Benowitz, Lessov, Jacob, Tyndale, Wilhelmsen: "Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence." in: Pharmacogenetics and genomics, Vol. 15, Issue 2, pp. 115-25, (2005) (PubMed).

Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).

Yamano, Tatsuno, Gonzalez: "The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes." in: Biochemistry, Vol. 29, Issue 5, pp. 1322-9, (1990) (PubMed).

Miles, Bickmore, Brook, McLaren, Meehan, Wolf: "Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity." in: Nucleic acids research, Vol. 17, Issue 8, pp. 2907-17, (1989) (PubMed).

Yamano, Nagata, Yamazoe, Kato, Gelboin, Gonzalez: "cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)." in: Nucleic acids research, Vol. 17, Issue 12, pp. 4888, (1989) (PubMed).

Aliases for CYP2A6 抗体

cytochrome P450 family 2 subfamily A member 6 (CYP2A6) 抗体
cytochrome P450 2A6 (CYP2A6) 抗体
cytochrome P450 family 2 subfamily A member 6 L homeolog (cyp2a6.L) 抗体
CPA6 抗体
CYP2A 抗体
CYP2A3 抗体
cyp2a6 抗体
CYPIIA6 抗体
P450C2A 抗体
P450PB 抗体
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