CYP27A1 产品
(Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008].
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Featured CYP27A1 Categories
CYP27A1 抗体
High quality antibodies with extensive validation data.
CYP27A1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CYP27A1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP27A1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN2855688
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7170770
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7236729
Quantity
200 μL
Datasheet
Datasheet
Recommended CYP27A1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955255
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1159814
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1159815
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP27A1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350952
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407904
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2712758
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our CYP27A1 Products
: "Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients." in: Medicine, Vol. 95, Issue 27, pp. e3926, (2016) (PubMed).: "Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).
: "Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells." in: Gut, Vol. 60, Issue 2, pp. 225-37, (2011) (PubMed).
: "Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study." in: Reproduction (Cambridge, England), Vol. 140, Issue 5, pp. 767-76, (2011) (PubMed).
: "The first cerebrotendinous xanthomatosis family from Argentina: a new mutation in CYP27A1 gene." in: Neurology, Vol. 70, Issue 5, pp. 402-4, (2008) (PubMed).
Synonyms and alternative names related to CYP27A1
cytochrome P450 family 27 subfamily A member 1 (CYP27A1), cytochrome P450, family 27, subfamily a, polypeptide 1 (Cyp27a1), cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), sterol 26-hydroxylase, mitochondrial (CYP27A1), cytochrome P450, family 27, subfamily A, polypeptide 1 (cyp27a1), 1300013A03Rik, CP27, CTX, CYP27, Cyp27, P450C27Protein level used designations for CYP27A1
- 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase
- 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase
- 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
- cholestanetriol 26-monooxygenase
- cytochrome P-450C27/25
- cytochrome P450 27
- cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1
- sterol 26-hydroxylase, mitochondrial
- sterol 27-hydroxylase
- vitamin D(3) 25-hydroxylase
- cytochrome P-450c27/25
- cholesterol 27 hydroxylase
- cytochrome P450, 27
- cytochrome P450, 27a1
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