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Cyclin T1 产品

(Cyclin T1 (CCNT1))

Categories

This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Featured Cyclin T1 Categories

Cyclin T1 抗体

High quality antibodies with extensive validation data.

Cyclin T1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Cyclin T1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cyclin T1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN4886509
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN654626
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2792158
Quantity 100 μL
Datasheet Datasheet

Recommended Cyclin T1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773959
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743055
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1769063
Quantity 96 tests
Datasheet Datasheet

Recommended Cyclin T1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348487
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1989589
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3090693
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Cyclin T1 Products

Kapasi, Clark, Tran, Spector: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." in: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, (2009) (PubMed).

Sun, Zheng, Zhao, Lee, Goldstein: "Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysaccharide" in: Journal of virology, Vol. 82, Issue 11, pp. 5562-72, (2008) (PubMed).

Synonyms and alternative names related to Cyclin T1

Cyclin T (CycT), cyclin T1 (CCNT1), cyclin T1 (ccnt1), cyclin T1 (Ccnt1), cyclin T1 L homeolog (ccnt1.L), 2810478G24Rik, AI115585, anon-74EFc, ccnt, CCNT, CG6292, Cyclin-T1, cyct1, CYCT1, CycT1, Dmcyclin T, Dmel\\CG6292, dT, fi75b02, HIVE1, ORE-14, P-TEFb, p124, si:dkey-18f23.10, wu:fi75b02

Protein level used designations for Cyclin T1

  • CG6292-PA
  • CG6292-PB
  • CG6292-PC
  • CG6292-PD
  • CycT-PA
  • CycT-PB
  • CycT-PC
  • CycT-PD
  • CyclinT
  • cyclin T
  • cyclin T1
  • cyclin T2
  • dCyclin T
  • cyclin-T1-like
  • CDK9-associated C-type protein
  • cyclin C-related protein
  • cyclin-T1
  • human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
  • cyclin-T
  • cycT1
  • cyclin T1 protein
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