Cyclin T1 产品
(Cyclin T1 (CCNT1))
Categories
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].
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Featured Cyclin T1 Categories
Cyclin T1 抗体
High quality antibodies with extensive validation data.
Cyclin T1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Cyclin T1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cyclin T1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN4886509
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN654626
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
- (3)
Cat. No.
ABIN2792158
Quantity
100 μL
Datasheet
Datasheet
Recommended Cyclin T1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773959
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743055
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1769063
Quantity
96 tests
Datasheet
Datasheet
Recommended Cyclin T1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348487
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1989589
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090693
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Cyclin T1 Products
: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." in: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, (2009) (PubMed).: "Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysaccharide" in: Journal of virology, Vol. 82, Issue 11, pp. 5562-72, (2008) (PubMed).
Synonyms and alternative names related to Cyclin T1
Cyclin T (CycT), cyclin T1 (CCNT1), cyclin T1 (ccnt1), cyclin T1 (Ccnt1), cyclin T1 L homeolog (ccnt1.L), 2810478G24Rik, AI115585, anon-74EFc, ccnt, CCNT, CG6292, Cyclin-T1, cyct1, CYCT1, CycT1, Dmcyclin T, Dmel\\CG6292, dT, fi75b02, HIVE1, ORE-14, P-TEFb, p124, si:dkey-18f23.10, wu:fi75b02Protein level used designations for Cyclin T1
- CG6292-PA
- CG6292-PB
- CG6292-PC
- CG6292-PD
- CycT-PA
- CycT-PB
- CycT-PC
- CycT-PD
- CyclinT
- cyclin T
- cyclin T1
- cyclin T2
- dCyclin T
- cyclin-T1-like
- CDK9-associated C-type protein
- cyclin C-related protein
- cyclin-T1
- human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
- cyclin-T
- cycT1
- cyclin T1 protein
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