Cyclin-Dependent Kinase 9 抗体
(Cyclin-Dependent Kinase 9 (CDK9))
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008].
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Latest Publications for our Cyclin-Dependent Kinase 9 抗体
: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).
: "Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription." in: Journal of virology, Vol. 80, Issue 10, pp. 4781-91, (2006) (PubMed).
: "The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription." in: Molecular cell, Vol. 19, Issue 4, pp. 523-34, (2005) (PubMed).
: "Differential localization and expression of the Cdk9 42k and 55k isoforms." in: Journal of cellular physiology, Vol. 203, Issue 1, pp. 251-60, (2005) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 34527-30, (2000) (PubMed).
: "Binding of CDK9 to TRAF2." in: Journal of cellular biochemistry, Vol. 71, Issue 4, pp. 467-78, (1999) (PubMed).
: "CDK9 (PITALRE): a multifunctional cdc2-related kinase." in: Journal of cellular physiology, Vol. 177, Issue 4, pp. 501-6, (1999) (PubMed).
: "The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat." in: Journal of virology, Vol. 72, Issue 9, pp. 7154-9, (1998) (PubMed).
Aliases for Cyclin-Dependent Kinase 9 抗体
cyclin dependent kinase 9 (CDK9) 抗体cyclin-dependent kinase 9 (CDC2-related kinase) (cdk9) 抗体
cyclin-dependent kinase 9 L homeolog (cdk9.L) 抗体
cyclin-dependent kinase 9 (Cdk9) 抗体
Cyclin-dependent kinase 9 (Cdk9) 抗体
cyclin-dependent kinase 9 (cdk9) 抗体
cyclin-dependent kinase 9 (CDC2-related kinase) (Cdk9) 抗体
cyclin dependent kinase 9 (Cdk9) 抗体
cyclin-dependent kinase 9 S homeolog (cdk9.S) 抗体
C-2k 抗体
c-2k 抗体
CDC2L4 抗体
cdc2l4 抗体
cdk9 抗体
CDK9 抗体
CG5179 抗体
CTK1 抗体
ctk1 抗体
Dmel\\CG5179 抗体
P-TEF 抗体
P-TEFb 抗体
PITALRE 抗体
pitalre 抗体
PTefb 抗体
TAK 抗体
tak 抗体
wu:fb22e09 抗体
wu:fc06c02 抗体
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