Cyclin-Dependent Kinase 9 产品
(Cyclin-Dependent Kinase 9 (CDK9))
Categories
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008].
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Featured Cyclin-Dependent Kinase 9 Categories
Cyclin-Dependent Kinase 9 抗体
High quality antibodies with extensive validation data.
Cyclin-Dependent Kinase 9 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Cyclin-Dependent Kinase 9 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cyclin-Dependent Kinase 9 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ChIP-seq
Validations
- (7)
Cat. No.
ABIN7266597
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (5)
Cat. No.
ABIN3015519
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
- (4)
Cat. No.
ABIN969042
Quantity
100 μL
Datasheet
Datasheet
Recommended Cyclin-Dependent Kinase 9 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1114469
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1114470
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN778482
Quantity
96 tests
Datasheet
Datasheet
Recommended Cyclin-Dependent Kinase 9 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1776650
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348986
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416046
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cyclin-Dependent Kinase 9 Products
: "Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription." in: Circulation. Heart failure, Vol. 8, Issue 1, pp. 138-48, (2015) (PubMed).: "The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition." in: PLoS genetics, Vol. 11, Issue 5, pp. e1005121, (2015) (PubMed).
: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).
: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).
: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).
: "Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription." in: Journal of virology, Vol. 80, Issue 10, pp. 4781-91, (2006) (PubMed).
: "The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription." in: Molecular cell, Vol. 19, Issue 4, pp. 523-34, (2005) (PubMed).
: "Differential localization and expression of the Cdk9 42k and 55k isoforms." in: Journal of cellular physiology, Vol. 203, Issue 1, pp. 251-60, (2005) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 34527-30, (2000) (PubMed).
Synonyms and alternative names related to Cyclin-Dependent Kinase 9
cyclin dependent kinase 9 (CDK9), cyclin-dependent kinase 9 (CDC2-related kinase) (cdk9), cyclin-dependent kinase 9 L homeolog (cdk9.L), cyclin-dependent kinase 9 (Cdk9), Cyclin-dependent kinase 9 (Cdk9), cyclin-dependent kinase 9 (cdk9), cyclin-dependent kinase 9 (CDC2-related kinase) (Cdk9), cyclin dependent kinase 9 (Cdk9), cyclin-dependent kinase 9 S homeolog (cdk9.S), C-2k, c-2k, CDC2L4, cdc2l4, cdk9, CDK9, CG5179, CTK1, ctk1, Dmel\\CG5179, P-TEF, P-TEFb, PITALRE, pitalre, PTefb, TAK, tak, wu:fb22e09, wu:fc06c02Protein level used designations for Cyclin-Dependent Kinase 9
- CDC2-related kinase
- cell division cycle 2-like protein kinase 4
- cell division protein kinase 9
- serine/threonine protein kinase PITALRE
- serine/threonine-protein kinase PITALRE
- tat-associated kinase complex catalytic subunit
- cyclin-dependent kinase 9 (CDC2-related kinase)
- cell division protein kinase 9-B
- cyclin-dependent kinase 9-B
- CG5179-PA
- Cdk9-PA
- Cyclin-dependent kinase9 2.7
- p43 PITALRE
- positive transcription elongation factor b
- positive transcription elongation factor b, small subunit
- cyclin-dependent kinase 9
- cell division protein kinase 9-A
- cyclin-dependent kinase 9-A
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