CYBB 抗体
(Cytochrome B-245, beta Polypeptide (CYBB))
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008].
recommended
CYBB 适用: 人, 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Reactivity
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Validations
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Chicken, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Application
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Quantity
100 μg
Datasheet
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Reactivity
Human, Mouse, Rat
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), IF, ICC
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN5692996
Quantity
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Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN750690
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Rabbit, Rat
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN908688
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Rabbit, Rat
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Rabbit, Rat
Application
WB, FACS, IF (cc), IF (p)
Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our CYBB 抗体
: "Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress." in: Redox biology, Vol. 32, pp. 101500, (2020) (PubMed).: "Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6825452, (2019) (PubMed).
: "Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation." in: Scientific reports, Vol. 6, pp. 30146, (2018) (PubMed).
: "CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation." in: International journal of oncology, Vol. 52, Issue 4, pp. 1209-1223, (2018) (PubMed).
: "Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 4596746, (2018) (PubMed).
: "Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in ..." in: Behavioural brain research, Vol. 339, pp. 19-27, (2017) (PubMed).
: "Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity." in: Scientific reports, Vol. 6, pp. 23135, (2017) (PubMed).
: "Obligatory role for GPER in cardiovascular aging and disease." in: Science signaling, Vol. 9, Issue 452, pp. ra105, (2017) (PubMed).
: "Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis." in: European journal of pharmacology, Vol. 771, pp. 114-22, (2016) (PubMed).
: "Amyloid β-induced astrogliosis is mediated by β1-integrin via NADPH oxidase 2 in Alzheimer's disease." in: Aging cell, (2016) (PubMed).
Aliases for CYBB 抗体
cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) 抗体cytochrome b-245, beta polypeptide (cybb) 抗体
cytochrome b-245 heavy chain (CYBB) 抗体
cytochrome b-245, beta polypeptide L homeolog (cybb.L) 抗体
cytochrome b-245, beta polypeptide (CYBB) 抗体
cytochrome b-245 beta polypeptide (CYBB) 抗体
cytochrome b-245 beta chain (CYBB) 抗体
cytochrome b-245, beta polypeptide (Cybb) 抗体
cytochrome b-245 beta chain (Cybb) 抗体
cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) 抗体
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