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CYBA 产品

(Cytochrome B-245, alpha Polypeptide (CYBA))

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Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008].

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Featured CYBA Categories

CYBA 抗体

High quality antibodies with extensive validation data.

CYBA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYBA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (5)
  • (2)
Cat. No. ABIN750538
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7149098
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1042639
Quantity 0.1 mL
Datasheet Datasheet

Recommended CYBA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1461093
Quantity 1 mg
Datasheet Datasheet
Reactivity Bison
Source Yeast
Validations
Cat. No. ABIN1641404
Quantity 1 mg
Datasheet Datasheet
Reactivity Pig
Source Yeast
Validations
Cat. No. ABIN1472559
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CYBA Products

Song, Zhang, Han, Zhang, Zhang, Gao, Zhang, Chu, Zhao: "Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 945-956, (2019) (PubMed).

Aurelius, Hallner, Werlenius, Riise, Möllgård, Brune, Hansson, Martner, Thorén, Hellstrand: "NOX2-dependent immunosuppression in chronic myelomonocytic leukemia." in: Journal of leukocyte biology, (2017) (PubMed).

Yue, Wang, Wang, Du, Shen, Tang, Wang, Yin: "Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways." in: International journal of biological macromolecules, Vol. 89, pp. 376-88, (2016) (PubMed).

Yoshida, Murayama, Kawashima, Nagahara, Kangawa, Mizukami, Kimura, Abe, Hayashi, Shibutani: "Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, Vol. 69, Issue 1, pp. 9-16, (2016) (PubMed).

Li, Wang, Zhu, Zhang, Pan, Wang et al.: "Arctigenin suppresses transforming growth factor-?1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen ..." in: Free radical research, Vol. 49, Issue 9, pp. 1095-113, (2015) (PubMed).

Walton, Shin, Tajinda, Heusner, Kogan, Miyake, Chen, Tamura, Matsumoto: "Adult neurogenesis transiently generates oxidative stress." in: PLoS ONE, Vol. 7, Issue 4, pp. e35264, (2012) (PubMed).

Taylor, Jesaitis: "Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics." in: Methods in molecular biology (Clifton, N.J.), Vol. 412, pp. 429-37, (2008) (PubMed).

Taniguchi, Ohno: "ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 601-8, (2008) (PubMed).

Taylor, Burritt, Baniulis, Foubert, Lord, Dinauer, Parkos, Jesaitis: "Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 12, pp. 7349-57, (2004) (PubMed).

Burritt, Busse, Gizachew, Siemsen, Quinn, Bond, Dratz, Jesaitis: "Antibody imprint of a membrane protein surface. Phagocyte flavocytochrome b." in: The Journal of biological chemistry, Vol. 273, Issue 38, pp. 24847-52, (1998) (PubMed).

Synonyms and alternative names related to CYBA

cytochrome b-245, alpha polypeptide (cyba), cytochrome b-245 alpha polypeptide L homeolog (cyba.L), cytochrome b-245, alpha polypeptide (CYBA), cytochrome b-245 alpha polypeptide (cyba), cytochrome b-245 light chain-like (LOC101328418), cytochrome b-245 alpha chain (CYBA), cytochrome b-245, alpha polypeptide (Cyba), cytochrome b-245 alpha chain (Cyba), p22-phox (CYBA), b558, CYBA, MGC80750, nmf333, p22-phox, p22-PHOX, P22-PHOX, p22phox, zgc:66077

Protein level used designations for CYBA

  • P22phox
  • cytochrome b-245, alpha polypeptide
  • predicted cytochrome b-245, alpha polypeptide
  • Cytochrome b(558) alpha chain
  • Cytochrome b558 subunit alpha
  • Neutrophil cytochrome b 22 kDa polypeptide
  • Superoxide-generating NADPH oxidase light chain subunit
  • cytochrome b-245 light chain
  • flavocytochrome b558 (p22phox)
  • p22 phagocyte B-cytochrome
  • cytochrome b light chain
  • cytochrome b(558) alpha chain
  • cytochrome b(558) alpha-subunit
  • cytochrome b, alpha polypeptide
  • cytochrome b558 subunit alpha
  • flavocytochrome b-558 alpha polypeptide
  • neutrophil cytochrome b 22 kDa polypeptide
  • p22phox
  • superoxide-generating NADPH oxidase light chain subunit
  • cytochrome beta-558
  • p22 phox
  • p22-phox
  • cytochrome b558 alpha-subunit
  • NADPH oxidase light chain subunit
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