CTLA4 抗体
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
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CTLA4 抗体 by Grade
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CTLA4 抗体 by 适用
Find CTLA4 抗体 for a variety of species such as anti-Human CTLA4, anti-Mouse CTLA4, anti-Rat CTLA4. The species listed below are among those available. Click on a link to go to the corresponding products.
CTLA4 抗体 by 抗体来源
Find CTLA4 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
CTLA4 抗体 by 克隆形成能力
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CTLA4 抗体 by Fragment
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Popular CTLA4 抗体
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Reactivity
Application
Validations
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Datasheet
Reactivity
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Application
WB, ELISA, IF
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Cat. No.
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Quantity
100 μg
Datasheet
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Reactivity
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Application
FACS
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Cat. No.
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Quantity
100 tests
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Cat. No.
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Quantity
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Application
FACS, IP, ICC, IHC (fro)
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Cat. No.
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Quantity
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Human
Application
FACS, IP, ICC, IHC (fro)
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Cat. No.
ABIN1981873
Quantity
0.1 mg
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Quantity
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Application
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
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Application
FACS, WB, ELISA, IHC (p), IF (p)
Validations
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Cat. No.
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Quantity
100 tests
Datasheet
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Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN7477429
Quantity
1 mL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN5518903
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Quantity
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Datasheet
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Latest Publications for our CTLA4 抗体
: "Immune signature as predictive marker for response to checkpoint inhibitor immunotherapy and overall survival in melanoma." in: Cancer medicine, (2021) (PubMed).: "Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models." in: American journal of cancer research, Vol. 9, Issue 1, pp. 53-63, (2019) (PubMed).
: "High CTLA-4 expression correlates with poor prognosis in thymoma patients." in: Oncotarget, Vol. 9, Issue 24, pp. 16665-16677, (2018) (PubMed).
: "Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease." in: Cancer immunology, immunotherapy : CII, Vol. 67, Issue 8, pp. 1297-1303, (2018) (PubMed).
: "Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats." in: Biochimica et biophysica acta, Vol. 1863, Issue 10 Pt B, pp. 2584-2593, (2017) (PubMed).
: "PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC)." in: Oncotarget, Vol. 8, Issue 16, pp. 26845-26857, (2017) (PubMed).
: "Prognostic impact of immune microenvironment in laryngeal and pharyngeal squamous cell carcinoma: Immune cell subtypes, immuno-suppressive pathways and clinicopathologic characteristics." in: Oncotarget, Vol. 8, Issue 12, pp. 19310-19322, (2017) (PubMed).
: "Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis." in: EJNMMI research, Vol. 6, Issue 1, pp. 1, (2016) (PubMed).
: "Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. ..." in: Oncoimmunology, Vol. 5, Issue 5, pp. e1100789, (2016) (PubMed).
: "Histamine suppresses regulatory T cells mediated by TGF-? in murine chronic allergic contact dermatitis." in: Experimental dermatology, Vol. 24, Issue 4, pp. 280-4, (2015) (PubMed).
Aliases for CTLA4 抗体
cytotoxic T-lymphocyte associated protein 4 (CTLA4) 抗体cytotoxic T-lymphocyte-associated protein 4 (Ctla4) 抗体
CD 抗体
CD152 抗体
Cd152 抗体
CELIAC3 抗体
CTLA-4 抗体
Ctla-4 抗体
CTLA4 抗体
GRD4 抗体
GSE 抗体
IDDM12 抗体
Ly-56 抗体
sCTLA4 抗体
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