CTCFL 产品
(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
Categories
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].
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Featured CTCFL Categories
CTCFL 抗体
High quality antibodies with extensive validation data.
CTCFL ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CTCFL 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CTCFL 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7172781
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ChIP-seq, ChIP
Validations
- (2)
Cat. No.
ABIN6971455
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN129668
Quantity
100 μg
Datasheet
Datasheet
Recommended CTCFL ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6965537
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5594143
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6225336
Quantity
96 tests
Datasheet
Datasheet
Recommended CTCFL 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122188
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350632
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091944
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CTCFL Products
: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." in: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).: "Expression of cancer/testis antigens is correlated with improved survival in glioblastoma." in: Oncotarget, Vol. 4, Issue 4, pp. 636-46, (2013) (PubMed).
: "A cell cycle role for the epigenetic factor CTCF-L/BORIS." in: PLoS ONE, Vol. 7, Issue 6, pp. e39371, (2012) (PubMed).
: "Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 9, pp. 1841-50, (2012) (PubMed).
: "CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 225-33, (2011) (PubMed).
: "Widespread expression of BORIS/CTCFL in normal and cancer cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22399, (2011) (PubMed).
: "BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 13, pp. 4267-76, (2011) (PubMed).
: "BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas." in: PLoS ONE, Vol. 5, Issue 3, pp. e9738, (2010) (PubMed).
: "Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development." in: Molecular human reproduction, Vol. 14, Issue 6, pp. 347-55, (2008) (PubMed).
: "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS." in: Biochemical and biophysical research communications, Vol. 370, Issue 1, pp. 109-12, (2008) (PubMed).
Synonyms and alternative names related to CTCFL
CCCTC-binding factor like (CTCFL), CCCTC-binding factor (zinc finger protein)-like (Ctcfl), CCCTC-binding factor like (Ctcfl), BORIS, Boris, CT27, CTCF-T, CTCFL, dJ579F20.2, HMGB1L1, OTTMUSG00000016680Protein level used designations for CTCFL
- BORIS-like protein
- CTCF paralog
- CTCF-like protein
- HMG-1L1
- brother of the regulator of imprinted sites
- cancer/testis antigen 27
- putative high mobility group protein 1-like 1
- putative high mobility group protein B1-like 1
- transcriptional repressor CTCFL
- zinc finger protein CTCF-T
- CCCTC-binding factor (zinc finger protein)-like
- CCCTC-binding factor-like protein
- BORIS
- Brother of the regulator of imprinted sites
- likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL)
- brother of regulator of imprinted sites
- transcriptional repressor CTCFL-like
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