CSK 抗体
(C-Src tyrosine Kinase (CSK))
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
recommended
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated
recommended
recommended
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Popular CSK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p), RNAi
Validations
- (8)
Cat. No.
ABIN560501
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7101334
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN184606
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, ICC, FACS
Validations
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- (3)
Cat. No.
ABIN969069
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN7211357
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7444412
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
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Cat. No.
ABIN7174015
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6243612
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN3184105
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IP, ICC
Validations
- (2)
Cat. No.
ABIN94268
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
Cat. No.
ABIN1679381
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7265975
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN3042764
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), ICC, IHC (fro)
Validations
- (1)
Cat. No.
ABIN1714331
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (p), IF (cc), IHC (p), ICC, FACS, IHC (fro)
Validations
- (1)
Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our CSK 抗体
: "Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase." in: Scientific reports, Vol. 3, pp. 926, (2013) (PubMed).: "Beta-catenin inhibits melanocyte migration but induces melanoma metastasis." in: Oncogene, Vol. 32, Issue 17, pp. 2230-8, (2013) (PubMed).
: "Genome-wide association study of blood pressure and hypertension. ..." in: Nature genetics, Vol. 41, Issue 6, pp. 677-87, (2010) (PubMed).
: "Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study." in: Journal of hypertension, Vol. 29, Issue 1, pp. 62-9, (2010) (PubMed).
: "A high-throughput candidate gene mutation screen in lymphoproliferative and myeloproliferative neoplasias." in: Leukemia research, Vol. 33, Issue 9, pp. e168-9, (2009) (PubMed).
: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).
: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).
: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).
: "The COOH-terminal Src kinase Csk is a tumor antigen in human carcinoma." in: Cancer research, Vol. 61, Issue 4, pp. 1415-20, (2001) (PubMed).
: "Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of ..." in: The Journal of biological chemistry, Vol. 274, Issue 4, pp. 2291-7, (1999) (PubMed).
Aliases for CSK 抗体
C-terminal Src kinase (CSK) 抗体c-src tyrosine kinase (Csk) 抗体
C-terminal Src kinase (Csk) 抗体
c-src tyrosine kinase (CSK) 抗体
CSK, non-receptor tyrosine kinase (CSK) 抗体
AW212630 抗体
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